Thoracic Surgery

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Research outputs of the Thoracic Surgery team at the RD&E.

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    A diagnostic cohort study on the accuracy of 18-fluorodeoxyglucose (18FDG) positron emission tomography (PET)-CT for evaluation of malignancy in anterior mediastinal lesions: the DECiMaL study.
    (BMJ, 2018-02) Proli, C.; De Sousa, P.; Jordan, S.; Anikin, V.; Devaraj, A.; Love, S. M.; Shackcloth, M.; Kostoulas, N.; Papagiannopoulos, K.; Haqzad, Y.; Loubani, M.; Sellitri, Francesco; Granato, F.; Bush, A.; Marchbank, A.; Iyer, S.; Scarci, M.; Lim, E.
    The aim of this study is to collate multi-institutional data to determine the value by defining the diagnostic performance of fluorodeoxyglucose positron emission tomography (FDG PET)/CT for malignancy in patients undergoing surgery with an anterior mediastinal mass in order to ascertain the clinical utility of PET/CT to differentiate malignant from benign aetiologies in patients presenting with an anterior mediastinal mass SETTING: DECiMaL Study is a multicentre, retrospective, collaborative cohort study in seven UK surgical sites.
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    Assessment and comparison of recovery after open and minimally invasive esophagectomy for cancer: an exploratory study in two centers.
    (Springer, 2013-06) Parameswaran, R; Titcomb, D R; Blencowe, N S; Berrisford, Richard G.; Wajed, Shahjehan A.; Streets, C G; Hollowood, A D; Krysztopik, R; Barham, C P; Blazeby, J M
    Minimally invasive esophagectomy (MIE) may lead to early restoration of health-related quality of life, but few prospective comparative studies have been performed. This exploratory study compared recovery between totally minimally invasive esophagectomy (MIE), laparoscopically assisted esophagectomy (LAE) and open surgery (OE).
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    Indwelling pleural catheters for non-malignant effusions: a multicentre review of practice
    (BMJ, 2014-10-01) Bhatnagar, R.; Reid, E. D.; Corcoran, J. P.; Bagenal, J. D.; Pope, Sandra; Clive, A. O.; Zahan-Evans, N.; Froeschle, Peter O.; West, D.; Rahman, N. M.; Chatterji, S.; Sivasothy, P. R.; Maskell, N. A.
    Indwelling pleural catheters (IPCs) are commonly used in the management of malignant pleural effusion (MPE). There is little data on their use in non-malignant conditions. All IPC insertions for non-malignant cases from five large UK centres were found using prospectively maintained databases. Data were collected on 57 IPC insertions. The commonest indications were hepatic hydrothorax (33%) and inflammatory pleuritis (26%). The mean weekly fluid output was 2.8 L (SD 2.52). 48/57 (84%) patients had no complications. Suspected pleural infection was documented in 2 (3.5%) cases. 33% (19/57) of patients underwent 'spontaneous' pleurodesis at a median time of 71 days. Patients with hepatic disease achieved pleurodesis significantly less often than those with non-hepatic disease (p=0.03). These data support the use of IPCs in select cases of non-malignant disease when maximal medical therapy has failed.