A Pilot Study of Dietary Nitrate Supplementation in Anaemic Patients.

2.50
Hdl Handle:
http://hdl.handle.net/11287/583452
Title:
A Pilot Study of Dietary Nitrate Supplementation in Anaemic Patients.
Authors:
Veale, Dave; Winyard, P; Vanhatalo, A; Jones, A; Kerr, Paul
Abstract:
Anaemia affects 60-90% of people with cancer. A lower haemoglobin (Hb) is associated with a worse quality of life. Erythropoietin treatment improves both Hb and quality of life but is associated with significant risk. Blood transfusions improve Hb but only have a short-term effect on quality of life. Stored blood has a reduced NO bioavailability causing reduced vasodilation, reduced blood flow and oxygen delivery to muscles, and reduced exercise tolerance and muscle oxidative function. Dietary nitrate supplementation has been shown to be of significant benefit in healthy individuals. It improves mitochondrial efficiency, reduces metabolic rate, increases blood flow to areas of the body requiring more oxygen, and reduces the effect of hypoxia on exercise capacity and muscle recovery.
Issue Date:
5-Nov-2015
URI:
http://hdl.handle.net/11287/583452
Type:
Meetings and Proceedings
Language:
en
Description:
Conference poster presented at Clinical Trials Symposium, RD&E 5/11/15.
Sponsors:
Research funded by Exeter Leukaemia Fund, Royal Devon & Exeter NHS Foundation Trust and the University of Exeter.
Appears in Collections:
2015 RD&E publications; Clinical Haematology; Oncology

Full metadata record

DC FieldValue Language
dc.contributor.authorVeale, Daveen
dc.contributor.authorWinyard, Pen
dc.contributor.authorVanhatalo, Aen
dc.contributor.authorJones, Aen
dc.contributor.authorKerr, Paulen
dc.date.accessioned2015-12-09T12:04:32Zen
dc.date.available2015-12-09T12:04:32Zen
dc.date.issued2015-11-05en
dc.identifier.urihttp://hdl.handle.net/11287/583452en
dc.descriptionConference poster presented at Clinical Trials Symposium, RD&E 5/11/15.en
dc.description.abstractAnaemia affects 60-90% of people with cancer. A lower haemoglobin (Hb) is associated with a worse quality of life. Erythropoietin treatment improves both Hb and quality of life but is associated with significant risk. Blood transfusions improve Hb but only have a short-term effect on quality of life. Stored blood has a reduced NO bioavailability causing reduced vasodilation, reduced blood flow and oxygen delivery to muscles, and reduced exercise tolerance and muscle oxidative function. Dietary nitrate supplementation has been shown to be of significant benefit in healthy individuals. It improves mitochondrial efficiency, reduces metabolic rate, increases blood flow to areas of the body requiring more oxygen, and reduces the effect of hypoxia on exercise capacity and muscle recovery.en
dc.description.sponsorshipResearch funded by Exeter Leukaemia Fund, Royal Devon & Exeter NHS Foundation Trust and the University of Exeter.en
dc.language.isoenen
dc.titleA Pilot Study of Dietary Nitrate Supplementation in Anaemic Patients.en
dc.typeMeetings and Proceedingsen
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