An international survey of screening and management of hypothyroidism during pregnancy in Latin America

2.50
Hdl Handle:
http://hdl.handle.net/11287/593827
Title:
An international survey of screening and management of hypothyroidism during pregnancy in Latin America
Authors:
Medeiros, M. F.; Cerqueira, T. L.; Silva Junior, J. C.; Amaral, M. T.; Vaidya, Bijay; Poppe, K. G.; Carvalho, G. A.; Gutierrez, S.; Alcaraz, G.; Abalovich, M.; Ramos, H. E.; Latin American Thyroid, Society
Abstract:
OBJECTIVE: To determine how endocrinologists in Latin America deal with clinical case scenarios related to hypothyroidism and pregnancy. MATERIALS AND METHODS: In January 2013, we sent an electronic questionnaire on current practice relating to management of hypothyroidism in pregnancy to 856 members of the Latin American Thyroid Society (LATS) who manage pregnant patients with thyroid disease. Subsequently, we have analyzed responses from physician members. RESULTS: Two hundred and ninety-three responders represent clinicians from 13 countries. All were directly involved in the management of maternal hypothyroidism and 90.7% were endocrinologists. The recommendation of a starting dose of L-thyoxine for a woman diagnosed with overt hypothyroidism in pregnancy, preconception management of euthyroid women with known thyroid autoimmunity and approach related to ovarian hyperstimulation in women with thyroid peroxidase antibodies were widely variable. For women with known hypothyroidism, 34.6% of responders would increase L-thyroxine dose by 30-50% as soon as pregnancy is confirmed. With regard to screening, 42.7% of responders perform universal evaluation and 70% recommend TSH < 2.5 mUI/L in the first trimester and TSH < 3 mUI/L in the second and third trimester as target results in known hypothyroid pregnant women. CONCLUSION: Deficiencies in diagnosis and management of hypothyroidism during pregnancy were observed in our survey, highlighting the need for improvement of specialist education and quality of care offered to patients with thyroid disease during pregnancy in Latin America.
Citation:
Arq Bras Endocrinol Metabol. 2014 Dec;58(9):906-11.
Publisher:
Arq Bras Endocrinol Metabol
Journal:
Arquivos brasileiros de endocrinologia e metabologia
Issue Date:
1-Dec-2014
URI:
http://hdl.handle.net/11287/593827
DOI:
10.1590/0004-2730000003382
PubMed ID:
25627045
Additional Links:
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302014000900906&lng=en&nrm=iso&tlng=en
Note:
This article is available via Open Access. Please click on the 'Additional Link' above to access the full-text.
Type:
Journal Article; Research Support, Non-U.S. Gov't
Language:
eng
ISSN:
1677-9487
Appears in Collections:
2014 RD&E publications; Diabetes/Endocrine Services

Full metadata record

DC FieldValue Language
dc.contributor.authorMedeiros, M. F.en
dc.contributor.authorCerqueira, T. L.en
dc.contributor.authorSilva Junior, J. C.en
dc.contributor.authorAmaral, M. T.en
dc.contributor.authorVaidya, Bijayen
dc.contributor.authorPoppe, K. G.en
dc.contributor.authorCarvalho, G. A.en
dc.contributor.authorGutierrez, S.en
dc.contributor.authorAlcaraz, G.en
dc.contributor.authorAbalovich, M.en
dc.contributor.authorRamos, H. E.en
dc.contributor.authorLatin American Thyroid, Societyen
dc.date.accessioned2016-01-19T12:35:27Zen
dc.date.available2016-01-19T12:35:27Zen
dc.date.issued2014-12-01en
dc.identifier.citationArq Bras Endocrinol Metabol. 2014 Dec;58(9):906-11.en
dc.identifier.issn1677-9487en
dc.identifier.pmid25627045en
dc.identifier.doi10.1590/0004-2730000003382en
dc.identifier.urihttp://hdl.handle.net/11287/593827en
dc.description.abstractOBJECTIVE: To determine how endocrinologists in Latin America deal with clinical case scenarios related to hypothyroidism and pregnancy. MATERIALS AND METHODS: In January 2013, we sent an electronic questionnaire on current practice relating to management of hypothyroidism in pregnancy to 856 members of the Latin American Thyroid Society (LATS) who manage pregnant patients with thyroid disease. Subsequently, we have analyzed responses from physician members. RESULTS: Two hundred and ninety-three responders represent clinicians from 13 countries. All were directly involved in the management of maternal hypothyroidism and 90.7% were endocrinologists. The recommendation of a starting dose of L-thyoxine for a woman diagnosed with overt hypothyroidism in pregnancy, preconception management of euthyroid women with known thyroid autoimmunity and approach related to ovarian hyperstimulation in women with thyroid peroxidase antibodies were widely variable. For women with known hypothyroidism, 34.6% of responders would increase L-thyroxine dose by 30-50% as soon as pregnancy is confirmed. With regard to screening, 42.7% of responders perform universal evaluation and 70% recommend TSH < 2.5 mUI/L in the first trimester and TSH < 3 mUI/L in the second and third trimester as target results in known hypothyroid pregnant women. CONCLUSION: Deficiencies in diagnosis and management of hypothyroidism during pregnancy were observed in our survey, highlighting the need for improvement of specialist education and quality of care offered to patients with thyroid disease during pregnancy in Latin America.en
dc.language.isoengen
dc.publisherArq Bras Endocrinol Metabolen
dc.relation.urlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302014000900906&lng=en&nrm=iso&tlng=enen
dc.titleAn international survey of screening and management of hypothyroidism during pregnancy in Latin Americaen
dc.typeJournal Articleen
dc.typeResearch Support, Non-U.S. Gov'ten
dc.identifier.journalArquivos brasileiros de endocrinologia e metabologiaen
dc.description.noteThis article is available via Open Access. Please click on the 'Additional Link' above to access the full-text.en

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