A prospective and nationwide study investigating endophthalmitis following pars plana vitrectomy: clinical presentation, microbiology, management and outcome

2.50
Hdl Handle:
http://hdl.handle.net/11287/593867
Title:
A prospective and nationwide study investigating endophthalmitis following pars plana vitrectomy: clinical presentation, microbiology, management and outcome
Authors:
Park, Jonathan C.; Ramasamy, B.; Shaw, S.; Ling, Roland H.; Prasad, S.
Abstract:
BACKGROUND/AIMS: This is the first prospective and nationwide study aiming to provide epidemiological data relating to presentation, microbiology, management and outcome of endophthalmitis following vitrectomy. METHODS: Two years of prospective and nationwide surveillance for cases of presumed infectious endophthalmitis within 6 weeks of pars plana vitrectomy was completed. The study obtained case reports via the established British Ophthalmological Surveillance Unit (BOSU) system. RESULTS: Thirty-seven cases were reported and 28 met the diagnostic criteria for presumed infectious endophthalmitis following vitrectomy. Mean age was 61 years and 67% were male. Nineteen cases were 23/25 gauge and 9 cases were 20 gauge. Mean time from surgery to endophthalmitis was 5 days. Blurred vision (85.2%), pain (77.8%) and a hypopyon (77.8%) were the commonest presenting symptoms and signs. Seventeen cases (60.7%) had a positive culture. Culture-positive endophthalmitis, relative to culture-negative endophthalmitis, was no different with respect to time to presentation, symptoms, signs or outcome. Outcome was poor, with 29.6% of eyes being eviscerated or having no perception of light or perception of light. CONCLUSIONS: This study helps surgeons promptly identify cases of endophthalmitis following vitrectomy and informs them about the various management options currently used and the likely outcome of this devastating complication.
Citation:
Br J Ophthalmol. 2014 Aug;98(8):1080-6.
Publisher:
BMJ
Journal:
The British journal of ophthalmology
Issue Date:
1-Aug-2014
URI:
http://hdl.handle.net/11287/593867
DOI:
10.1136/bjophthalmol-2013-304486
PubMed ID:
24686917
Additional Links:
http://bjo.bmj.com/cgi/pmidlookup?view=long&pmid=24686917
Note:
RD&E staff can access the full-text of this article by clicking on the 'Additional Link' above and logging in with NHS OpenAthens if prompted.
Type:
Journal Article; Research Support, Non-U.S. Gov't
Language:
eng
ISSN:
1468-2079
Appears in Collections:
Ophthalmology (West of England Eye Unit); 2014 RD&E publications

Full metadata record

DC FieldValue Language
dc.contributor.authorPark, Jonathan C.en
dc.contributor.authorRamasamy, B.en
dc.contributor.authorShaw, S.en
dc.contributor.authorLing, Roland H.en
dc.contributor.authorPrasad, S.en
dc.date.accessioned2016-01-19T12:36:01Zen
dc.date.available2016-01-19T12:36:01Zen
dc.date.issued2014-08-01en
dc.identifier.citationBr J Ophthalmol. 2014 Aug;98(8):1080-6.en
dc.identifier.issn1468-2079en
dc.identifier.pmid24686917en
dc.identifier.doi10.1136/bjophthalmol-2013-304486en
dc.identifier.urihttp://hdl.handle.net/11287/593867en
dc.description.abstractBACKGROUND/AIMS: This is the first prospective and nationwide study aiming to provide epidemiological data relating to presentation, microbiology, management and outcome of endophthalmitis following vitrectomy. METHODS: Two years of prospective and nationwide surveillance for cases of presumed infectious endophthalmitis within 6 weeks of pars plana vitrectomy was completed. The study obtained case reports via the established British Ophthalmological Surveillance Unit (BOSU) system. RESULTS: Thirty-seven cases were reported and 28 met the diagnostic criteria for presumed infectious endophthalmitis following vitrectomy. Mean age was 61 years and 67% were male. Nineteen cases were 23/25 gauge and 9 cases were 20 gauge. Mean time from surgery to endophthalmitis was 5 days. Blurred vision (85.2%), pain (77.8%) and a hypopyon (77.8%) were the commonest presenting symptoms and signs. Seventeen cases (60.7%) had a positive culture. Culture-positive endophthalmitis, relative to culture-negative endophthalmitis, was no different with respect to time to presentation, symptoms, signs or outcome. Outcome was poor, with 29.6% of eyes being eviscerated or having no perception of light or perception of light. CONCLUSIONS: This study helps surgeons promptly identify cases of endophthalmitis following vitrectomy and informs them about the various management options currently used and the likely outcome of this devastating complication.en
dc.language.isoengen
dc.publisherBMJen
dc.relation.urlhttp://bjo.bmj.com/cgi/pmidlookup?view=long&pmid=24686917en
dc.titleA prospective and nationwide study investigating endophthalmitis following pars plana vitrectomy: clinical presentation, microbiology, management and outcomeen
dc.typeJournal Articleen
dc.typeResearch Support, Non-U.S. Gov'ten
dc.identifier.journalThe British journal of ophthalmologyen
dc.description.noteRD&E staff can access the full-text of this article by clicking on the 'Additional Link' above and logging in with NHS OpenAthens if prompted.en

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