A role for panendoscopy? Second primary tumour in early stage squamous cell carcinoma of the oral tongue

2.50
Hdl Handle:
http://hdl.handle.net/11287/593920
Title:
A role for panendoscopy? Second primary tumour in early stage squamous cell carcinoma of the oral tongue
Authors:
Koo, K.; Harris, Robert; Wiesenfeld, D.; Iseli, T. A.
Abstract:
BACKGROUND: Panendoscopy is routinely used for the identification of occult second primary tumours in head and neck squamous cell carcinoma. However, its role in low risk subgroups, particularly non-smoking, non-drinking patients and patients presenting with early stage oral cavity lesions, is debatable. METHODS: The records of 112 patients with T(1) or T(2) oral tongue squamous cell carcinoma were retrospectively reviewed. Demographic, disease characteristics and survival data were collected. RESULTS: Average follow-up duration was 71.7 months (range, 3.6-238.3 months). Thirty-five patients died within this period. Thirteen second primary events were identified in 11 patients, with all but 2 tumours in the oral cavity or oropharynx. There was a single synchronous primary - a lung adenocarcinoma; all other events were metachronous. No non-smoking, non-drinking patients re-presented with a second primary tumour; tobacco and alcohol use are clearly risk factors for development of a second primary tumour. CONCLUSION: The role of panendoscopy for identifying synchronous primary tumours in patients with early stage oral tongue squamous cell carcinoma should be re-evaluated, particularly in non-smoking, non-drinking patients who are at low risk of second primary development. Close follow up with regular clinical examination including flexible fibre-optic endoscopy may be sufficient in this subgroup.
Citation:
J Laryngol Otol. 2015 Jan;129 Suppl 1:S27-31.
Publisher:
Cambridge Journals
Journal:
The Journal of laryngology and otology
Issue Date:
1-Jan-2015
URI:
http://hdl.handle.net/11287/593920
DOI:
10.1017/S0022215114002989
PubMed ID:
25656280
Additional Links:
http://journals.cambridge.org/abstract_S0022215114002989
Type:
Journal Article
Language:
eng
ISSN:
1748-5460
Appears in Collections:
2015 RD&E publications; ENT (Ear, Nose & Throat)

Full metadata record

DC FieldValue Language
dc.contributor.authorKoo, K.en
dc.contributor.authorHarris, Roberten
dc.contributor.authorWiesenfeld, D.en
dc.contributor.authorIseli, T. A.en
dc.date.accessioned2016-01-19T12:37:22Zen
dc.date.available2016-01-19T12:37:22Zen
dc.date.issued2015-01-01en
dc.identifier.citationJ Laryngol Otol. 2015 Jan;129 Suppl 1:S27-31.en
dc.identifier.issn1748-5460en
dc.identifier.pmid25656280en
dc.identifier.doi10.1017/S0022215114002989en
dc.identifier.urihttp://hdl.handle.net/11287/593920en
dc.description.abstractBACKGROUND: Panendoscopy is routinely used for the identification of occult second primary tumours in head and neck squamous cell carcinoma. However, its role in low risk subgroups, particularly non-smoking, non-drinking patients and patients presenting with early stage oral cavity lesions, is debatable. METHODS: The records of 112 patients with T(1) or T(2) oral tongue squamous cell carcinoma were retrospectively reviewed. Demographic, disease characteristics and survival data were collected. RESULTS: Average follow-up duration was 71.7 months (range, 3.6-238.3 months). Thirty-five patients died within this period. Thirteen second primary events were identified in 11 patients, with all but 2 tumours in the oral cavity or oropharynx. There was a single synchronous primary - a lung adenocarcinoma; all other events were metachronous. No non-smoking, non-drinking patients re-presented with a second primary tumour; tobacco and alcohol use are clearly risk factors for development of a second primary tumour. CONCLUSION: The role of panendoscopy for identifying synchronous primary tumours in patients with early stage oral tongue squamous cell carcinoma should be re-evaluated, particularly in non-smoking, non-drinking patients who are at low risk of second primary development. Close follow up with regular clinical examination including flexible fibre-optic endoscopy may be sufficient in this subgroup.en
dc.language.isoengen
dc.publisherCambridge Journalsen
dc.relation.urlhttp://journals.cambridge.org/abstract_S0022215114002989en
dc.titleA role for panendoscopy? Second primary tumour in early stage squamous cell carcinoma of the oral tongueen
dc.typeJournal Articleen
dc.identifier.journalThe Journal of laryngology and otologyen

Related articles on PubMed

All Items in RD&E Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.