Clival osteomyelitis and hypoglossal nerve palsy-rare complications of Lemierre's syndrome

2.50
Hdl Handle:
http://hdl.handle.net/11287/593986
Title:
Clival osteomyelitis and hypoglossal nerve palsy-rare complications of Lemierre's syndrome
Authors:
He, J.; Lam, J. C.; Adlan, Tarig
Abstract:
An increasingly reported entity, Lemierre's syndrome classically presents with a recent oropharyngeal infection, internal jugular vein thrombosis and the presence of anaerobic organisms such as Fusobacterium necrophorum. The authors report a normally fit and well 17-year-old boy who presented with severe sepsis following a 5-day history of a sore throat, myalgia and neck stiffness requiring intensive care admission. Blood cultures grew F. necrophorum and radiological investigations demonstrated left internal jugular vein, cavernous sinus and sigmoid sinus thrombus, left vertebral artery dissection and thrombus within the left internal carotid artery. Imaging also revealed two areas of acute ischaemia in the brain, consistent with septic emboli, skull base (clival) osteomyelitis and an extensive epidural abscess. The patient improved on meropenem and metronidazole and was warfarinised for his cavernous sinus thrombosis. He has an on-going left-sided hypoglossal (XIIth) nerve palsy.
Citation:
BMJ Case Rep. 2015 Aug 30;2015
Publisher:
BMJ
Journal:
BMJ case reports
Issue Date:
30-Aug-2015
URI:
http://hdl.handle.net/11287/593986
DOI:
10.1136/bcr-2015-209777
PubMed ID:
26323975
Additional Links:
http://casereports.bmj.com/cgi/pmidlookup?view=long&pmid=26323975
Note:
RD&E staff can access the full-text of this article by clicking on the 'Additional Link' above and logging in with NHS OpenAthens if prompted.
Type:
Case Report
Language:
eng
ISSN:
1757-790X
Appears in Collections:
2015 RD&E publications; Radiology Department

Full metadata record

DC FieldValue Language
dc.contributor.authorHe, J.en
dc.contributor.authorLam, J. C.en
dc.contributor.authorAdlan, Tarigen
dc.date.accessioned2016-01-19T12:38:17Zen
dc.date.available2016-01-19T12:38:17Zen
dc.date.issued2015-08-30en
dc.identifier.citationBMJ Case Rep. 2015 Aug 30;2015en
dc.identifier.issn1757-790Xen
dc.identifier.pmid26323975en
dc.identifier.doi10.1136/bcr-2015-209777en
dc.identifier.urihttp://hdl.handle.net/11287/593986en
dc.description.abstractAn increasingly reported entity, Lemierre's syndrome classically presents with a recent oropharyngeal infection, internal jugular vein thrombosis and the presence of anaerobic organisms such as Fusobacterium necrophorum. The authors report a normally fit and well 17-year-old boy who presented with severe sepsis following a 5-day history of a sore throat, myalgia and neck stiffness requiring intensive care admission. Blood cultures grew F. necrophorum and radiological investigations demonstrated left internal jugular vein, cavernous sinus and sigmoid sinus thrombus, left vertebral artery dissection and thrombus within the left internal carotid artery. Imaging also revealed two areas of acute ischaemia in the brain, consistent with septic emboli, skull base (clival) osteomyelitis and an extensive epidural abscess. The patient improved on meropenem and metronidazole and was warfarinised for his cavernous sinus thrombosis. He has an on-going left-sided hypoglossal (XIIth) nerve palsy.en
dc.language.isoengen
dc.publisherBMJen
dc.relation.urlhttp://casereports.bmj.com/cgi/pmidlookup?view=long&pmid=26323975en
dc.titleClival osteomyelitis and hypoglossal nerve palsy-rare complications of Lemierre's syndromeen
dc.typeCase Reporten
dc.identifier.journalBMJ case reportsen
dc.description.noteRD&E staff can access the full-text of this article by clicking on the 'Additional Link' above and logging in with NHS OpenAthens if prompted.en

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