Tranexamic acid in major trauma: implementation and evaluation across South West England

2.50
Hdl Handle:
http://hdl.handle.net/11287/593989
Title:
Tranexamic acid in major trauma: implementation and evaluation across South West England
Authors:
Paudyal, P.; Smith, J.; Robinson, M.; South, A.; Higginson, I.; Reuben, Adam; Shaffee, J.; Black, S.; Logan, Stuart
Abstract:
OBJECTIVE: To carry out a prospective evaluation of tranexamic acid (TXA) use in trauma patients. PATIENTS AND METHODS: TXA was introduced to all emergency ambulances and emergency departments in the South West, UK, on 1 December 2011. We carried out a prospective evaluation of TXA use in trauma patients in the South West Peninsula between December 2011 and December 2012. We collected prehospital and hospital data on TXA administration using the Trauma Audit Research Network database. Data on prehospital administration of TXA were cross-checked with the South Western Ambulance Service Trust. Data were analysed using SPSS (version 20). RESULTS: Altogether, 82 patients were administered TXA during the study period. The median age of the patients was 49 years (IQR 30, 66), and 72% were men. One-third of the patients arrived at hospital by air ambulance. During the first 3 months, administration of TXA was limited to one patient each month receiving the drug. However, an upward trend was observed after June until October 2012, with the increment being more than 10 fold in July, September and October 2012. CONCLUSION: This is the first study to evaluate the use of TXA in civilian practice in the UK. Our study shows that ambulance service personnel and emergency departments can effectively administer TXA.
Citation:
Eur J Emerg Med. 2015 Aug 26.
Publisher:
Wolters Kluwer
Journal:
European journal of emergency medicine : official journal of the European Society for Emergency Medicine
Issue Date:
26-Aug-2015
URI:
http://hdl.handle.net/11287/593989
DOI:
10.1097/MEJ.0000000000000323
PubMed ID:
26313316
Additional Links:
http://dx.doi.org/10.1097/MEJ.0000000000000323
Type:
Journal Article
Language:
Eng
ISSN:
1473-5695
Appears in Collections:
2015 RD&E publications; Honorary contracts publications

Full metadata record

DC FieldValue Language
dc.contributor.authorPaudyal, P.en
dc.contributor.authorSmith, J.en
dc.contributor.authorRobinson, M.en
dc.contributor.authorSouth, A.en
dc.contributor.authorHigginson, I.en
dc.contributor.authorReuben, Adamen
dc.contributor.authorShaffee, J.en
dc.contributor.authorBlack, S.en
dc.contributor.authorLogan, Stuarten
dc.date.accessioned2016-01-19T12:38:19Zen
dc.date.available2016-01-19T12:38:19Zen
dc.date.issued2015-08-26en
dc.identifier.citationEur J Emerg Med. 2015 Aug 26.en
dc.identifier.issn1473-5695en
dc.identifier.pmid26313316en
dc.identifier.doi10.1097/MEJ.0000000000000323en
dc.identifier.urihttp://hdl.handle.net/11287/593989en
dc.description.abstractOBJECTIVE: To carry out a prospective evaluation of tranexamic acid (TXA) use in trauma patients. PATIENTS AND METHODS: TXA was introduced to all emergency ambulances and emergency departments in the South West, UK, on 1 December 2011. We carried out a prospective evaluation of TXA use in trauma patients in the South West Peninsula between December 2011 and December 2012. We collected prehospital and hospital data on TXA administration using the Trauma Audit Research Network database. Data on prehospital administration of TXA were cross-checked with the South Western Ambulance Service Trust. Data were analysed using SPSS (version 20). RESULTS: Altogether, 82 patients were administered TXA during the study period. The median age of the patients was 49 years (IQR 30, 66), and 72% were men. One-third of the patients arrived at hospital by air ambulance. During the first 3 months, administration of TXA was limited to one patient each month receiving the drug. However, an upward trend was observed after June until October 2012, with the increment being more than 10 fold in July, September and October 2012. CONCLUSION: This is the first study to evaluate the use of TXA in civilian practice in the UK. Our study shows that ambulance service personnel and emergency departments can effectively administer TXA.en
dc.language.isoEngen
dc.publisherWolters Kluweren
dc.relation.urlhttp://dx.doi.org/10.1097/MEJ.0000000000000323en
dc.titleTranexamic acid in major trauma: implementation and evaluation across South West Englanden
dc.typeJournal Articleen
dc.identifier.journalEuropean journal of emergency medicine : official journal of the European Society for Emergency Medicineen

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