Elevated polygenic burden for autism is associated with differential DNA methylation at birth.

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Authors
Hannon, E.
Mill, Jonathan
Journal
Genome medicine
Type
Journal Article
Publisher
BioMed Central
Rights
Archived with thanks to Genome medicine
Autism spectrum disorder (ASD) is a severe neurodevelopmental disorder characterized by deficits in social communication and restricted, repetitive behaviors, interests, or activities. The etiology of ASD involves both inherited and environmental risk factors, with epigenetic processes hypothesized as one mechanism by which both genetic and non-genetic variation influence gene regulation and pathogenesis. The aim of this study was to identify DNA methylation biomarkers of ASD detectable at birth.
Citation
Elevated polygenic burden for autism is associated with differential DNA methylation at birth. 2018, 10 (1):19 Genome Med
Note
This article is freely available via Open Access. Click on the Additional Link above to access the full-text via the publisher's site.