The regenerative role of adipose-derived stem cells (ADSC) in plastic and reconstructive surgery.

4.50
Hdl Handle:
http://hdl.handle.net/11287/595965
Title:
The regenerative role of adipose-derived stem cells (ADSC) in plastic and reconstructive surgery.
Authors:
Naderi, N; Combellack, E J; Griffin, M; Sedaghati, T; Javed, M; Findlay, M W; Wallace, Christopher G ( 0000-0003-1897-9520 ) ; Mosahebi, A; Butler, P E; Seifalian, A M; Whitaker, I S
Abstract:
The potential use of stem cell-based therapies for the repair and regeneration of various tissues and organs offers a paradigm shift in plastic and reconstructive surgery. The use of either embryonic stem cells (ESC) or induced pluripotent stem cells (iPSC) in clinical situations is limited because of regulations and ethical considerations even though these cells are theoretically highly beneficial. Adult mesenchymal stem cells appear to be an ideal stem cell population for practical regenerative medicine. Among these cells, adipose-derived stem cells (ADSC) have the potential to differentiate the mesenchymal, ectodermal and endodermal lineages and are easy to harvest. Additionally, adipose tissue yields a high number of ADSC per volume of tissue. Based on this background knowledge, the purpose of this review is to summarise and describe the proliferation and differentiation capacities of ADSC together with current preclinical data regarding the use of ADSC as regenerative tools in plastic and reconstructive surgery.
Citation:
The regenerative role of adipose-derived stem cells (ADSC) in plastic and reconstructive surgery. 2017 Feb;14(1):112-124
Publisher:
Wiley
Journal:
International wound journal
Issue Date:
Feb-2017
URI:
http://hdl.handle.net/11287/595965
DOI:
10.1111/iwj.12569
PubMed ID:
26833722
Additional Links:
http://dx.doi.org/10.1111/iwj.12569
Type:
Journal Article
ISSN:
1742-481X
Appears in Collections:
Plastic & Reconstructive Surgery; 2016 RD&E publications

Full metadata record

DC FieldValue Language
dc.contributor.authorNaderi, Nen
dc.contributor.authorCombellack, E Jen
dc.contributor.authorGriffin, Men
dc.contributor.authorSedaghati, Ten
dc.contributor.authorJaved, Men
dc.contributor.authorFindlay, M Wen
dc.contributor.authorWallace, Christopher Gen
dc.contributor.authorMosahebi, Aen
dc.contributor.authorButler, P Een
dc.contributor.authorSeifalian, A Men
dc.contributor.authorWhitaker, I Sen
dc.date.accessioned2016-02-09T15:09:47Zen
dc.date.available2016-02-09T15:09:47Zen
dc.date.issued2017-02en
dc.identifier.citationThe regenerative role of adipose-derived stem cells (ADSC) in plastic and reconstructive surgery. 2017 Feb;14(1):112-124en
dc.identifier.issn1742-481Xen
dc.identifier.pmid26833722en
dc.identifier.doi10.1111/iwj.12569en
dc.identifier.urihttp://hdl.handle.net/11287/595965en
dc.description.abstractThe potential use of stem cell-based therapies for the repair and regeneration of various tissues and organs offers a paradigm shift in plastic and reconstructive surgery. The use of either embryonic stem cells (ESC) or induced pluripotent stem cells (iPSC) in clinical situations is limited because of regulations and ethical considerations even though these cells are theoretically highly beneficial. Adult mesenchymal stem cells appear to be an ideal stem cell population for practical regenerative medicine. Among these cells, adipose-derived stem cells (ADSC) have the potential to differentiate the mesenchymal, ectodermal and endodermal lineages and are easy to harvest. Additionally, adipose tissue yields a high number of ADSC per volume of tissue. Based on this background knowledge, the purpose of this review is to summarise and describe the proliferation and differentiation capacities of ADSC together with current preclinical data regarding the use of ADSC as regenerative tools in plastic and reconstructive surgery.en
dc.languageENGen
dc.publisherWileyen
dc.relation.urlhttp://dx.doi.org/10.1111/iwj.12569en
dc.rightsArchived with thanks to International wound journalen
dc.subjectWessex Classification Subject Headings::Surgery::Plastic surgeryen
dc.titleThe regenerative role of adipose-derived stem cells (ADSC) in plastic and reconstructive surgery.en
dc.typeJournal Articleen
dc.identifier.journalInternational wound journalen
dc.type.versionPublisheden
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