Echogenicity of the Common Carotid Artery Intima-Media Complex in Stroke.

2.50
Hdl Handle:
http://hdl.handle.net/11287/600956
Title:
Echogenicity of the Common Carotid Artery Intima-Media Complex in Stroke.
Authors:
Aizawa, Kunihiko; Elyas, Salim; Adingupu, D. D.; Casanova, Francesco; Gooding, Kim M.; Shore, Angela ( 0000-0003-3039-308x ) ; Strain, David; Gates, Phillip E.
Abstract:
The grey-scale median of the common carotid artery intima-media complex (IM-GSM) characterizes arterial wall composition, and a low IM-GSM is associated with increased cardiovascular mortality in the elderly. We aimed to determine differences in the IM-GSM between a cohort with cerebrovascular disease and a healthy cohort. Eighty-two healthy individuals (control group: 63.2 ± 8.7 y) and 96 patients with either stroke or transient ischemic attacks (CRVD group: 68.6 ± 9.8 y) were studied. Common carotid artery intima-media thickness and IM-GSM obtained by ultrasound were analyzed using semi-automated edge-detection software. The IM-GSM was significantly lower in the CRVD group than in the control group (106 ± 24 vs. 124 ± 27 au, p < 0.001). The IM-GSM was similar for the infarct and non-infarct sides in CRVD. In the pooled cohort of all participants, the lower the quartile of IM-GSM, the greater were the carotid artery intima-media thickness and carotid artery remodeling. These results suggest the presence of an altered atherosclerotic phenotype in the intima-media complex of CRVD patients that can be detected by ultrasound.
Citation:
Echogenicity of the Common Carotid Artery Intima-Media Complex in Stroke. 2016 May;42(5):1130-7
Publisher:
Elsevier
Journal:
Ultrasound in medicine & biology
Issue Date:
1-Mar-2016
URI:
http://hdl.handle.net/11287/600956
DOI:
10.1016/j.ultrasmedbio.2016.01.006
PubMed ID:
26944528
Additional Links:
http://linkinghub.elsevier.com/retrieve/pii/S0301-5629(16)00039-9
Type:
Journal Article
Language:
en
ISSN:
1879-291X
Appears in Collections:
Stroke; Diabetes/Endocrine Services; Cardiology; Honorary contracts publications; 2016 RD&E publications

Full metadata record

DC FieldValue Language
dc.contributor.authorAizawa, Kunihikoen
dc.contributor.authorElyas, Salimen
dc.contributor.authorAdingupu, D. D.en
dc.contributor.authorCasanova, Francescoen
dc.contributor.authorGooding, Kim M.en
dc.contributor.authorShore, Angelaen
dc.contributor.authorStrain, Daviden
dc.contributor.authorGates, Phillip E.en
dc.date.accessioned2016-03-08T16:27:33Zen
dc.date.available2016-03-08T16:27:33Zen
dc.date.issued2016-03-01en
dc.identifier.citationEchogenicity of the Common Carotid Artery Intima-Media Complex in Stroke. 2016 May;42(5):1130-7en
dc.identifier.issn1879-291Xen
dc.identifier.pmid26944528en
dc.identifier.doi10.1016/j.ultrasmedbio.2016.01.006en
dc.identifier.urihttp://hdl.handle.net/11287/600956en
dc.description.abstractThe grey-scale median of the common carotid artery intima-media complex (IM-GSM) characterizes arterial wall composition, and a low IM-GSM is associated with increased cardiovascular mortality in the elderly. We aimed to determine differences in the IM-GSM between a cohort with cerebrovascular disease and a healthy cohort. Eighty-two healthy individuals (control group: 63.2 ± 8.7 y) and 96 patients with either stroke or transient ischemic attacks (CRVD group: 68.6 ± 9.8 y) were studied. Common carotid artery intima-media thickness and IM-GSM obtained by ultrasound were analyzed using semi-automated edge-detection software. The IM-GSM was significantly lower in the CRVD group than in the control group (106 ± 24 vs. 124 ± 27 au, p < 0.001). The IM-GSM was similar for the infarct and non-infarct sides in CRVD. In the pooled cohort of all participants, the lower the quartile of IM-GSM, the greater were the carotid artery intima-media thickness and carotid artery remodeling. These results suggest the presence of an altered atherosclerotic phenotype in the intima-media complex of CRVD patients that can be detected by ultrasound.en
dc.languageENGen
dc.language.isoenen
dc.publisherElsevieren
dc.relation.urlhttp://linkinghub.elsevier.com/retrieve/pii/S0301-5629(16)00039-9en
dc.rightsArchived with thanks to Ultrasound in medicine & biologyen
dc.subjectWessex Classification Subject Headings::Cardiologyen
dc.subjectWessex Classification Subject Headings::Neurology::Strokeen
dc.titleEchogenicity of the Common Carotid Artery Intima-Media Complex in Stroke.en
dc.typeJournal Articleen
dc.identifier.journalUltrasound in medicine & biologyen
dc.type.versionIn press (epub ahead of print)en

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