Response to a pilot single-centre randomized trial: the PATRASTOM trial.

2.50
Hdl Handle:
http://hdl.handle.net/11287/603989
Title:
Response to a pilot single-centre randomized trial: the PATRASTOM trial.
Authors:
Murkin, C; Blazeby, J M; Blencowe, N; Rooshenas, L; Reeves, B; Daniels, Ian R. ( 0000-0002-9114-0812 ) ; Pinkney, T; Smart, Neil J. ( 0000-0002-3043-8324 )
Abstract:
We read the PATRASTOM pilot randomised controlled trial (RCT) paper (1) with great interest. Parastomal Hernia (PSH) prevention is an area needing high quality evidence. Good pre-trial work, such as pilot studies, has an important role in the design of definitive multi-centre trials. We have several methodological concerns, however, that limit the findings and interpretation of this study. Pilot studies aim to test the feasibility, reliability and validity of the proposed design of a main RCT [2]. As such, pilot RCTs are designed to establish whether, for example, it is possible to recruit and randomise patients, and whether the preferred end points in a main trial can be collected with acceptable completeness [3]. This article is protected by copyright. All rights reserved.
Citation:
Response to a pilot single-centre randomized trial: the PATRASTOM trial. 2016 Jun;18(6):622-3: Colorectal Dis
Publisher:
Wiley
Journal:
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
Issue Date:
23-Mar-2016
URI:
http://hdl.handle.net/11287/603989
DOI:
10.1111/codi.13338
PubMed ID:
27004980
Additional Links:
http://dx.doi.org/10.1111/codi.13338
Type:
Letter
Language:
en
ISSN:
1463-1318
Appears in Collections:
Colorectal Surgery; HeSRU publications; 2016 RD&E publications

Full metadata record

DC FieldValue Language
dc.contributor.authorMurkin, Cen
dc.contributor.authorBlazeby, J Men
dc.contributor.authorBlencowe, Nen
dc.contributor.authorRooshenas, Len
dc.contributor.authorReeves, Ben
dc.contributor.authorDaniels, Ian R.en
dc.contributor.authorPinkney, Ten
dc.contributor.authorSmart, Neil J.en
dc.date.accessioned2016-03-30T12:01:50Zen
dc.date.available2016-03-30T12:01:50Zen
dc.date.issued2016-03-23en
dc.identifier.citationResponse to a pilot single-centre randomized trial: the PATRASTOM trial. 2016 Jun;18(6):622-3: Colorectal Disen
dc.identifier.issn1463-1318en
dc.identifier.pmid27004980en
dc.identifier.doi10.1111/codi.13338en
dc.identifier.urihttp://hdl.handle.net/11287/603989en
dc.description.abstractWe read the PATRASTOM pilot randomised controlled trial (RCT) paper (1) with great interest. Parastomal Hernia (PSH) prevention is an area needing high quality evidence. Good pre-trial work, such as pilot studies, has an important role in the design of definitive multi-centre trials. We have several methodological concerns, however, that limit the findings and interpretation of this study. Pilot studies aim to test the feasibility, reliability and validity of the proposed design of a main RCT [2]. As such, pilot RCTs are designed to establish whether, for example, it is possible to recruit and randomise patients, and whether the preferred end points in a main trial can be collected with acceptable completeness [3]. This article is protected by copyright. All rights reserved.en
dc.languageENGen
dc.language.isoenen
dc.publisherWileyen
dc.relation.urlhttp://dx.doi.org/10.1111/codi.13338en
dc.rightsArchived with thanks to Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Irelanden
dc.subjectWessex Classification Subject Headings::Gastroenterologyen
dc.titleResponse to a pilot single-centre randomized trial: the PATRASTOM trial.en
dc.typeLetteren
dc.identifier.journalColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Irelanden
dc.type.versionIn press (epub ahead of print)en
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