A review of biocompatibility in hernia repair; considerations in vitro and in vivo for selecting the most appropriate repair material.

2.50
Hdl Handle:
http://hdl.handle.net/11287/604209
Title:
A review of biocompatibility in hernia repair; considerations in vitro and in vivo for selecting the most appropriate repair material.
Authors:
Bryan, N.; Battersby, C.; Smart, Neil J. ( 0000-0002-3043-8324 ) ; Hunt, J.
Abstract:
Repair of hernia typically makes use of a prosthetic material; synthetic or biologic in nature. Any material which enters the body is subject to interrogation by the inflammation and immune system in addition to numerous other cell families, the outcome of which ultimately determines the success of the repair. In this review, we discuss the fundamental biology which occurs in situ when a biomaterial associates with a tissue, compare and contrast the techniques available to predict this in vitro, and review how features of hernia repair materials specifically may manipulate tissue interrogation and integration. Finally, we conclude our article by examining how biocompatibility impacts surgical practise and how a better understanding of the manner by which materials and tissues interact could benefit hernia repair.
Citation:
A review of biocompatibility in hernia repair; considerations in vitro and in vivo for selecting the most appropriate repair material. 2015, 19 (2):169-78 Hernia
Publisher:
Springer
Journal:
Hernia : the journal of hernias and abdominal wall surgery
Issue Date:
Apr-2015
URI:
http://hdl.handle.net/11287/604209
DOI:
10.1007/s10029-014-1307-8
PubMed ID:
25216716
Additional Links:
http://dx.doi.org/10.1007/s10029-014-1307-8
Type:
Journal Article
Language:
en
ISSN:
1248-9204
Appears in Collections:
2015 RD&E publications; Colorectal Surgery; HeSRU publications

Full metadata record

DC FieldValue Language
dc.contributor.authorBryan, N.en
dc.contributor.authorBattersby, C.en
dc.contributor.authorSmart, Neil J.en
dc.contributor.authorHunt, J.en
dc.date.accessioned2016-04-01T11:52:56Zen
dc.date.available2016-04-01T11:52:56Zen
dc.date.issued2015-04en
dc.identifier.citationA review of biocompatibility in hernia repair; considerations in vitro and in vivo for selecting the most appropriate repair material. 2015, 19 (2):169-78 Herniaen
dc.identifier.issn1248-9204en
dc.identifier.pmid25216716en
dc.identifier.doi10.1007/s10029-014-1307-8en
dc.identifier.urihttp://hdl.handle.net/11287/604209en
dc.description.abstractRepair of hernia typically makes use of a prosthetic material; synthetic or biologic in nature. Any material which enters the body is subject to interrogation by the inflammation and immune system in addition to numerous other cell families, the outcome of which ultimately determines the success of the repair. In this review, we discuss the fundamental biology which occurs in situ when a biomaterial associates with a tissue, compare and contrast the techniques available to predict this in vitro, and review how features of hernia repair materials specifically may manipulate tissue interrogation and integration. Finally, we conclude our article by examining how biocompatibility impacts surgical practise and how a better understanding of the manner by which materials and tissues interact could benefit hernia repair.en
dc.language.isoenen
dc.publisherSpringeren
dc.relation.urlhttp://dx.doi.org/10.1007/s10029-014-1307-8en
dc.rightsArchived with thanks to Hernia : the journal of hernias and abdominal wall surgeryen
dc.subjectWessex Classification Subject Headings::Gastroenterologyen
dc.titleA review of biocompatibility in hernia repair; considerations in vitro and in vivo for selecting the most appropriate repair material.en
dc.typeJournal Articleen
dc.identifier.journalHernia : the journal of hernias and abdominal wall surgeryen
dc.type.versionPublisheden

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