Rapid Down-Regulation of Glucocorticoid Gene Expression in the Dentate Gyrus after Acute Stress in vivo: Role of DNA Methylation and microRNA Activity.

2.50
Hdl Handle:
http://hdl.handle.net/11287/605284
Title:
Rapid Down-Regulation of Glucocorticoid Gene Expression in the Dentate Gyrus after Acute Stress in vivo: Role of DNA Methylation and microRNA Activity.
Authors:
Mifsud, K. R.; Saunderson, E. A.; Spiers, H.; Carter, S. D.; Trollope, A. F.; Mill, Jonathan; Reul, J. M H M
Abstract:
Although glucocorticoid receptors (GRs) in the hippocampus play a vital role in the regulation of physiological and behavioural responses to stress, the regulation of receptor expression remains unclear. This work investigates the molecular mechanisms underpinning stress-induced changes in hippocampal GR mRNA levels in vivo.
Citation:
Rapid Down-Regulation of Glucocorticoid Gene Expression in the Dentate Gyrus after Acute Stress in vivo: Role of DNA Methylation and microRNA Activity. 2017;104(2):157-169. Epub 2016 Apr 8. Neuroendocrinology
Publisher:
Karger
Journal:
Neuroendocrinology
Issue Date:
8-Apr-2016
URI:
http://hdl.handle.net/11287/605284
DOI:
10.1159/000445875
PubMed ID:
27054829
Additional Links:
http://www.karger.com/?DOI=10.1159/000445875
Type:
Journal Article
Language:
en
ISSN:
1423-0194
Appears in Collections:
Honorary contracts publications; 2016 RD&E publications

Full metadata record

DC FieldValue Language
dc.contributor.authorMifsud, K. R.en
dc.contributor.authorSaunderson, E. A.en
dc.contributor.authorSpiers, H.en
dc.contributor.authorCarter, S. D.en
dc.contributor.authorTrollope, A. F.en
dc.contributor.authorMill, Jonathanen
dc.contributor.authorReul, J. M H Men
dc.date.accessioned2016-04-14T14:38:01Zen
dc.date.available2016-04-14T14:38:01Zen
dc.date.issued2016-04-08en
dc.identifier.citationRapid Down-Regulation of Glucocorticoid Gene Expression in the Dentate Gyrus after Acute Stress in vivo: Role of DNA Methylation and microRNA Activity. 2017;104(2):157-169. Epub 2016 Apr 8. Neuroendocrinologyen
dc.identifier.issn1423-0194en
dc.identifier.pmid27054829en
dc.identifier.doi10.1159/000445875en
dc.identifier.urihttp://hdl.handle.net/11287/605284en
dc.description.abstractAlthough glucocorticoid receptors (GRs) in the hippocampus play a vital role in the regulation of physiological and behavioural responses to stress, the regulation of receptor expression remains unclear. This work investigates the molecular mechanisms underpinning stress-induced changes in hippocampal GR mRNA levels in vivo.en
dc.languageENGen
dc.language.isoenen
dc.publisherKargeren
dc.relation.urlhttp://www.karger.com/?DOI=10.1159/000445875en
dc.rightsArchived with thanks to Neuroendocrinologyen
dc.subjectWessex Classification Subject Headings::Oncology. Pathology.::Geneticsen
dc.titleRapid Down-Regulation of Glucocorticoid Gene Expression in the Dentate Gyrus after Acute Stress in vivo: Role of DNA Methylation and microRNA Activity.en
dc.typeJournal Articleen
dc.identifier.journalNeuroendocrinologyen
dc.type.versionIn press (epub ahead of print)en
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