Multiple-digit periungual Bowen's disease: a novel treatment approach with radiotherapy.

2.50
Hdl Handle:
http://hdl.handle.net/11287/609973
Title:
Multiple-digit periungual Bowen's disease: a novel treatment approach with radiotherapy.
Authors:
Hunt, William T.; Cameron, A.; Craig, P.; de Berker, D. A.
Abstract:
Multiple periungual Bowen disease [BD; also known as squamous cell carcinoma (SCC) in situ] is rare. The pathogenesis of the disease is linked to human papilloma virus, and in some instances to chronic immunosuppression. The usual management of periungual BD is by local excision, Mohs micrographic surgery or distal phalanx amputation. Our patient was offered radiotherapy in the hope of maximizing residual function and minimizing morbidity from treatment. A good response was seen at 2 months post-radiotherapy, but this was followed by relapses at 4 and 6 months post-radiotherapy. Persistent anonychia resulted in improved access to the involved skin, making topical therapy possible. Radiotherapy can be a valuable management approach for periungual SCC/BD in locations where amputation could result in substantial disability.
Citation:
Multiple-digit periungual Bowen's disease: a novel treatment approach with radiotherapy. 2013, 38 (8):857-61 Clin. Exp. Dermatol.
Publisher:
Wiley
Journal:
Clinical and experimental dermatology
Issue Date:
13-Aug-2013
URI:
http://hdl.handle.net/11287/609973
DOI:
10.1111/ced.12149
PubMed ID:
23937119
Additional Links:
http://onlinelibrary.wiley.com/doi/10.1111/ced.12149/abstract;jsessionid=BA430228539DC6444C0846B32C5BCFF0.f04t04
Note:
This article is freely available via Open Access. Click on the 'Additional Link' above to access the full-text from the publisher's site.
Type:
Journal Article
Language:
en
ISSN:
1365-2230
Appears in Collections:
pre-2014 RD&E publications

Full metadata record

DC FieldValue Language
dc.contributor.authorHunt, William T.en
dc.contributor.authorCameron, A.en
dc.contributor.authorCraig, P.en
dc.contributor.authorde Berker, D. A.en
dc.date.accessioned2016-05-20T09:20:57Zen
dc.date.available2016-05-20T09:20:57Zen
dc.date.issued2013-08-13en
dc.identifier.citationMultiple-digit periungual Bowen's disease: a novel treatment approach with radiotherapy. 2013, 38 (8):857-61 Clin. Exp. Dermatol.en
dc.identifier.issn1365-2230en
dc.identifier.pmid23937119en
dc.identifier.doi10.1111/ced.12149en
dc.identifier.urihttp://hdl.handle.net/11287/609973en
dc.description.abstractMultiple periungual Bowen disease [BD; also known as squamous cell carcinoma (SCC) in situ] is rare. The pathogenesis of the disease is linked to human papilloma virus, and in some instances to chronic immunosuppression. The usual management of periungual BD is by local excision, Mohs micrographic surgery or distal phalanx amputation. Our patient was offered radiotherapy in the hope of maximizing residual function and minimizing morbidity from treatment. A good response was seen at 2 months post-radiotherapy, but this was followed by relapses at 4 and 6 months post-radiotherapy. Persistent anonychia resulted in improved access to the involved skin, making topical therapy possible. Radiotherapy can be a valuable management approach for periungual SCC/BD in locations where amputation could result in substantial disability.en
dc.language.isoenen
dc.publisherWileyen
dc.relation.urlhttp://onlinelibrary.wiley.com/doi/10.1111/ced.12149/abstract;jsessionid=BA430228539DC6444C0846B32C5BCFF0.f04t04en
dc.rightsArchived with thanks to Clinical and experimental dermatologyen
dc.subjectWessex Classification Subject Headings::Dermatologyen
dc.subjectWessex Classification Subject Headings::Oncology. Pathology.en
dc.titleMultiple-digit periungual Bowen's disease: a novel treatment approach with radiotherapy.en
dc.typeJournal Articleen
dc.identifier.journalClinical and experimental dermatologyen
dc.description.noteThis article is freely available via Open Access. Click on the 'Additional Link' above to access the full-text from the publisher's site.en
dc.type.versionPublisheden

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