Erythropoietin improves long-term neurological outcome in acute ischemic stroke patients: a randomized, prospective, placebo-controlled clinical trial.

2.50
Hdl Handle:
http://hdl.handle.net/11287/610860
Title:
Erythropoietin improves long-term neurological outcome in acute ischemic stroke patients: a randomized, prospective, placebo-controlled clinical trial.
Authors:
Tsai, T-H; Lu, C-H; Wallace, Christopher G ( 0000-0003-1897-9520 ) ; Chang, W-N; Chen, S-F; Huang, C-R; Tsai, N-W; Lan, M-Y; Sung, P-H; Liu, C-F; Yip, H-K
Abstract:
Mortality and disability following ischemic stroke (IS) remains unacceptably high with respect to the conventional therapies. This study tested the effect of erythropoietin (EPO) on long-term neurological outcome in patients after acute IS. This study aimed to evaluate the safety and efficacy of two consecutive doses of EPO (5,000 IU/dose, subcutaneously administered at 48 hours and 72 hours after acute IS) on improving the 90-day combined endpoint of recurrent stroke or death that has been previously reported. A secondary objective was to evaluate the long-term (that is, five years) outcome of patients who received EPO.
Citation:
Erythropoietin improves long-term neurological outcome in acute ischemic stroke patients: a randomized, prospective, placebo-controlled clinical trial. 2015, 19:49 Crit Care
Publisher:
BioMed Central
Journal:
Critical care (London, England)
Issue Date:
25-Feb-2015
URI:
http://hdl.handle.net/11287/610860
DOI:
10.1186/s13054-015-0761-8
PubMed ID:
25888250
Additional Links:
http://ccforum.biomedcentral.com/articles/10.1186/s13054-015-0761-8
Note:
This article is freely available via Open Access. Click on the 'Additional Link' above to access the full-text via the publisher's site.
Type:
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Language:
en
ISSN:
1466-609X
Appears in Collections:
2015 RD&E publications; Plastic & Reconstructive Surgery

Full metadata record

DC FieldValue Language
dc.contributor.authorTsai, T-Hen
dc.contributor.authorLu, C-Hen
dc.contributor.authorWallace, Christopher Gen
dc.contributor.authorChang, W-Nen
dc.contributor.authorChen, S-Fen
dc.contributor.authorHuang, C-Ren
dc.contributor.authorTsai, N-Wen
dc.contributor.authorLan, M-Yen
dc.contributor.authorSung, P-Hen
dc.contributor.authorLiu, C-Fen
dc.contributor.authorYip, H-Ken
dc.date.accessioned2016-05-27T11:06:13Z-
dc.date.available2016-05-27T11:06:13Z-
dc.date.issued2015-02-25-
dc.identifier.citationErythropoietin improves long-term neurological outcome in acute ischemic stroke patients: a randomized, prospective, placebo-controlled clinical trial. 2015, 19:49 Crit Careen
dc.identifier.issn1466-609X-
dc.identifier.pmid25888250-
dc.identifier.doi10.1186/s13054-015-0761-8-
dc.identifier.urihttp://hdl.handle.net/11287/610860-
dc.description.abstractMortality and disability following ischemic stroke (IS) remains unacceptably high with respect to the conventional therapies. This study tested the effect of erythropoietin (EPO) on long-term neurological outcome in patients after acute IS. This study aimed to evaluate the safety and efficacy of two consecutive doses of EPO (5,000 IU/dose, subcutaneously administered at 48 hours and 72 hours after acute IS) on improving the 90-day combined endpoint of recurrent stroke or death that has been previously reported. A secondary objective was to evaluate the long-term (that is, five years) outcome of patients who received EPO.en
dc.language.isoenen
dc.publisherBioMed Centralen
dc.relation.urlhttp://ccforum.biomedcentral.com/articles/10.1186/s13054-015-0761-8en
dc.rightsArchived with thanks to Critical care (London, England). This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.en
dc.subjectWessex Classification Subject Headings::Neurology::Strokeen
dc.titleErythropoietin improves long-term neurological outcome in acute ischemic stroke patients: a randomized, prospective, placebo-controlled clinical trial.en
dc.typeJournal Articleen
dc.typeRandomized Controlled Trialen
dc.typeResearch Support, Non-U.S. Gov'ten
dc.identifier.journalCritical care (London, England)en
dc.description.noteThis article is freely available via Open Access. Click on the 'Additional Link' above to access the full-text via the publisher's site.en
dc.type.versionPublisheden

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