Diagnosis of monogenic diabetes: 10-Year experience in a large multi-ethnic diabetes center.

2.50
Hdl Handle:
http://hdl.handle.net/11287/614441
Title:
Diagnosis of monogenic diabetes: 10-Year experience in a large multi-ethnic diabetes center.
Authors:
Thomas, E. R.; Brackenridge, A.; Kidd, J.; Kariyawasam, D.; Carroll, P.; Colclough, Kevin; Ellard, Sian ( 0000-0002-7620-5526 )
Abstract:
Monogenic diabetes accounts for approximately 1-2% of all diabetes, and is difficult to distinguish from type 1 and type 2 diabetes. Molecular diagnosis is important, as the molecular subtype directs appropriate treatment. Patients are selected for testing according to clinical criteria, but up to 80% of monogenic diabetes in the UK has not been correctly diagnosed. We investigated outcomes of genetic testing in our center to compare methods of selecting patients, and consider avenues to increase diagnostic efficiency.
Citation:
Diagnosis of monogenic diabetes: 10-Year experience in a large multi-ethnic diabetes center. 2016, 7 (3):332-7 J Diabetes Investig
Publisher:
Wiley
Journal:
Journal of diabetes investigation
Issue Date:
May-2016
URI:
http://hdl.handle.net/11287/614441
DOI:
10.1111/jdi.12432
PubMed ID:
27330718
Additional Links:
http://onlinelibrary.wiley.com/doi/10.1111/jdi.12432/full
Note:
This article is freely available online via Open Access. Click on the 'Additional Link' above to access the full-text via the publisher's site.
Type:
Journal Article
Language:
en
ISSN:
2040-1124
Appears in Collections:
Exeter Clinical Laboratory International (Blood Sciences, Genetics, Cellular Pathology & Microbiology); Molecular Genetics; 2016 RD&E publications

Full metadata record

DC FieldValue Language
dc.contributor.authorThomas, E. R.en
dc.contributor.authorBrackenridge, A.en
dc.contributor.authorKidd, J.en
dc.contributor.authorKariyawasam, D.en
dc.contributor.authorCarroll, P.en
dc.contributor.authorColclough, Kevinen
dc.contributor.authorEllard, Sianen
dc.date.accessioned2016-06-23T13:13:16Z-
dc.date.available2016-06-23T13:13:16Z-
dc.date.issued2016-05-
dc.identifier.citationDiagnosis of monogenic diabetes: 10-Year experience in a large multi-ethnic diabetes center. 2016, 7 (3):332-7 J Diabetes Investigen
dc.identifier.issn2040-1124-
dc.identifier.pmid27330718-
dc.identifier.doi10.1111/jdi.12432-
dc.identifier.urihttp://hdl.handle.net/11287/614441-
dc.description.abstractMonogenic diabetes accounts for approximately 1-2% of all diabetes, and is difficult to distinguish from type 1 and type 2 diabetes. Molecular diagnosis is important, as the molecular subtype directs appropriate treatment. Patients are selected for testing according to clinical criteria, but up to 80% of monogenic diabetes in the UK has not been correctly diagnosed. We investigated outcomes of genetic testing in our center to compare methods of selecting patients, and consider avenues to increase diagnostic efficiency.en
dc.language.isoenen
dc.publisherWileyen
dc.relation.urlhttp://onlinelibrary.wiley.com/doi/10.1111/jdi.12432/fullen
dc.rightsArchived with thanks to Journal of Diabetes Investigation. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.en
dc.subjectWessex Classification Subject Headings::Endocrinology::Diabetesen
dc.titleDiagnosis of monogenic diabetes: 10-Year experience in a large multi-ethnic diabetes center.en
dc.typeJournal Articleen
dc.identifier.journalJournal of diabetes investigationen
dc.description.noteThis article is freely available online via Open Access. Click on the 'Additional Link' above to access the full-text via the publisher's site.en
dc.type.versionPublisheden

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