Prophylactic radiotherapy for the prevention of procedure-tract metastases after surgical and large-bore pleural procedures in malignant pleural mesothelioma (SMART): a multicentre, open-label, phase 3, randomised controlled trial.

2.50
Hdl Handle:
http://hdl.handle.net/11287/615341
Title:
Prophylactic radiotherapy for the prevention of procedure-tract metastases after surgical and large-bore pleural procedures in malignant pleural mesothelioma (SMART): a multicentre, open-label, phase 3, randomised controlled trial.
Authors:
Clive, A. O.; Taylor, H.; Dobson, L.; Wilson, P.; de Winton, E.; Panakis, N.; Pepperell, J.; Howell, T.; Stewart, S. A.; Penz, E.; Jordan, N.; Morley, A. J.; Zahan-Evans, N.; Smith, S.; Batchelor, T. J. P.; Marchbank, A.; Bishop, L.; Ionescu, A. A.; Bayne, M.; Cooper, S.; Kerry, A.; Jenkins, P.; Toy, Elizabeth; Vigneswaran, V.; Gildersleve, J.; Ahmed, M.; McDonald, F.; Button, M.; Lewanski, C.; Comins, C.; Dakshinamoorthy, M.; Lee, Y. C. G.; Rahman, N. M.; Maskell, N. A.
Abstract:
The use of prophylactic radiotherapy to prevent procedure-tract metastases (PTMs) in malignant pleural mesothelioma remains controversial, and clinical practice varies worldwide. We aimed to compare prophylactic radiotherapy with deferred radiotherapy (given only when a PTM developed) in a suitably powered trial.
Citation:
Prophylactic radiotherapy for the prevention of procedure-tract metastases after surgical and large-bore pleural procedures in malignant pleural mesothelioma (SMART): a multicentre, open-label, phase 3, randomised controlled trial. 2016 Aug;17(8):1094-104: Lancet Oncol.
Publisher:
Elsevier
Journal:
The Lancet. Oncology
Issue Date:
23-Jun-2016
URI:
http://hdl.handle.net/11287/615341
DOI:
10.1016/S1470-2045(16)30095-X
PubMed ID:
27345639
Additional Links:
http://linkinghub.elsevier.com/retrieve/pii/S1470-2045(16)30095-X
Note:
This article is freely available via Open Access. Click on the 'Additional Link' above to access the full-text via the publisher's site.
Type:
Journal Article; Multicenter Study; Randomized Controlled Trial
Language:
en
ISSN:
1474-5488
Appears in Collections:
Oncology; 2016 RD&E publications

Full metadata record

DC FieldValue Language
dc.contributor.authorClive, A. O.en
dc.contributor.authorTaylor, H.en
dc.contributor.authorDobson, L.en
dc.contributor.authorWilson, P.en
dc.contributor.authorde Winton, E.en
dc.contributor.authorPanakis, N.en
dc.contributor.authorPepperell, J.en
dc.contributor.authorHowell, T.en
dc.contributor.authorStewart, S. A.en
dc.contributor.authorPenz, E.en
dc.contributor.authorJordan, N.en
dc.contributor.authorMorley, A. J.en
dc.contributor.authorZahan-Evans, N.en
dc.contributor.authorSmith, S.en
dc.contributor.authorBatchelor, T. J. P.en
dc.contributor.authorMarchbank, A.en
dc.contributor.authorBishop, L.en
dc.contributor.authorIonescu, A. A.en
dc.contributor.authorBayne, M.en
dc.contributor.authorCooper, S.en
dc.contributor.authorKerry, A.en
dc.contributor.authorJenkins, P.en
dc.contributor.authorToy, Elizabethen
dc.contributor.authorVigneswaran, V.en
dc.contributor.authorGildersleve, J.en
dc.contributor.authorAhmed, M.en
dc.contributor.authorMcDonald, F.en
dc.contributor.authorButton, M.en
dc.contributor.authorLewanski, C.en
dc.contributor.authorComins, C.en
dc.contributor.authorDakshinamoorthy, M.en
dc.contributor.authorLee, Y. C. G.en
dc.contributor.authorRahman, N. M.en
dc.contributor.authorMaskell, N. A.en
dc.date.accessioned2016-07-01T11:56:33Z-
dc.date.available2016-07-01T11:56:33Z-
dc.date.issued2016-06-23-
dc.identifier.citationProphylactic radiotherapy for the prevention of procedure-tract metastases after surgical and large-bore pleural procedures in malignant pleural mesothelioma (SMART): a multicentre, open-label, phase 3, randomised controlled trial. 2016 Aug;17(8):1094-104: Lancet Oncol.en
dc.identifier.issn1474-5488-
dc.identifier.pmid27345639-
dc.identifier.doi10.1016/S1470-2045(16)30095-X-
dc.identifier.urihttp://hdl.handle.net/11287/615341-
dc.description.abstractThe use of prophylactic radiotherapy to prevent procedure-tract metastases (PTMs) in malignant pleural mesothelioma remains controversial, and clinical practice varies worldwide. We aimed to compare prophylactic radiotherapy with deferred radiotherapy (given only when a PTM developed) in a suitably powered trial.en
dc.languageENG-
dc.language.isoenen
dc.publisherElsevieren
dc.relation.urlhttp://linkinghub.elsevier.com/retrieve/pii/S1470-2045(16)30095-Xen
dc.rightsArchived with thanks to The Lancet Oncology. Open Access article distributed under the terms of CC BY.en
dc.subjectWessex Classification Subject Headings::Oncology. Pathology.en
dc.titleProphylactic radiotherapy for the prevention of procedure-tract metastases after surgical and large-bore pleural procedures in malignant pleural mesothelioma (SMART): a multicentre, open-label, phase 3, randomised controlled trial.en
dc.typeJournal Articleen
dc.typeMulticenter Studyen
dc.typeRandomized Controlled Trialen
dc.identifier.journalThe Lancet. Oncologyen
dc.description.noteThis article is freely available via Open Access. Click on the 'Additional Link' above to access the full-text via the publisher's site.en
dc.type.versionIn press (epub ahead of print)en

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