The value of in vitro studies in a case of neonatal diabetes with a novel Kir6.2-W68G mutation.

2.50
Hdl Handle:
http://hdl.handle.net/11287/618137
Title:
The value of in vitro studies in a case of neonatal diabetes with a novel Kir6.2-W68G mutation.
Authors:
O'Connell, S. M.; Proks, P.; Kramer, H.; Mattis, K. K.; Sachse, G.; Joyce, C.; Houghton, J. A. L.; Ellard, Sian ( 0000-0002-7620-5526 ) ; Hattersley, Andrew T.; Ashcroft, F. M.; O'Riordan, S. M. P.
Abstract:
In infants, especially with novel previously undescribed mutations of the KATP channel causing neonatal diabetes, in vitro studies can be used to both predict the response to sulphonylurea treatment and support a second trial of glibenclamide at higher than standard doses if the expected response is not observed.
Citation:
The value of in vitro studies in a case of neonatal diabetes with a novel Kir6.2-W68G mutation. 2015, 3 (10):884-7 Clin Case Rep
Publisher:
Wiley
Journal:
Clinical case reports
Issue Date:
Oct-2015
URI:
http://hdl.handle.net/11287/618137
DOI:
10.1002/ccr3.370
PubMed ID:
26509030
Additional Links:
http://dx.doi.org/10.1002/ccr3.370
Note:
This article is freely available via the publisher's site - click on the 'Additional Link' above to access the full text.
Type:
Journal Article
Language:
en
ISSN:
2050-0904
Appears in Collections:
2015 RD&E publications; Diabetes/Endocrine Services; Molecular Genetics

Full metadata record

DC FieldValue Language
dc.contributor.authorO'Connell, S. M.en
dc.contributor.authorProks, P.en
dc.contributor.authorKramer, H.en
dc.contributor.authorMattis, K. K.en
dc.contributor.authorSachse, G.en
dc.contributor.authorJoyce, C.en
dc.contributor.authorHoughton, J. A. L.en
dc.contributor.authorEllard, Sianen
dc.contributor.authorHattersley, Andrew T.en
dc.contributor.authorAshcroft, F. M.en
dc.contributor.authorO'Riordan, S. M. P.en
dc.date.accessioned2016-08-09T14:50:02Z-
dc.date.available2016-08-09T14:50:02Z-
dc.date.issued2015-10-
dc.identifier.citationThe value of in vitro studies in a case of neonatal diabetes with a novel Kir6.2-W68G mutation. 2015, 3 (10):884-7 Clin Case Repen
dc.identifier.issn2050-0904-
dc.identifier.pmid26509030-
dc.identifier.doi10.1002/ccr3.370-
dc.identifier.urihttp://hdl.handle.net/11287/618137-
dc.description.abstractIn infants, especially with novel previously undescribed mutations of the KATP channel causing neonatal diabetes, in vitro studies can be used to both predict the response to sulphonylurea treatment and support a second trial of glibenclamide at higher than standard doses if the expected response is not observed.en
dc.language.isoenen
dc.publisherWileyen
dc.relation.urlhttp://dx.doi.org/10.1002/ccr3.370en
dc.rightsArchived with thanks to Clinical case reportsen
dc.subjectWessex Classification Subject Headings::Oncology. Pathology.::Geneticsen
dc.subjectWessex Classification Subject Headings::Endocrinology::Diabetesen
dc.titleThe value of in vitro studies in a case of neonatal diabetes with a novel Kir6.2-W68G mutation.en
dc.typeJournal Articleen
dc.identifier.journalClinical case reportsen
dc.description.noteThis article is freely available via the publisher's site - click on the 'Additional Link' above to access the full text.en
dc.type.versionPublisheden

Related articles on PubMed

All Items in RD&E Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.