Acute double flexor tendon ruptures following injection of collagenase clostridium histolyticum (Xiapex) for Dupuytren's contracture.

2.50
Hdl Handle:
http://hdl.handle.net/11287/619100
Title:
Acute double flexor tendon ruptures following injection of collagenase clostridium histolyticum (Xiapex) for Dupuytren's contracture.
Authors:
Povlsen, B.; Singh, Sarvpreet
Abstract:
We report a case of acute (24 h) double flexor tendon rupture of the little finger after a single injection of collagenase clostridium histolyticum into a palmar Dupuytren's contracture cord which caused metacarpophalangeal joint contracture. Tendon surgery was performed 48 h postinjury with primary repair and standard rehabilitation but it resulted in poor active flexion due to adhesions. Previous papers have suggested that a needle inserted into the flexor tendon can be detected prior to the injection of collagenase by asking the patient to actively move the finger, but our test on an awake patient showed that when a 27-gauge needle was inserted into the flexor tendons through a thick palmar cord, the syringe did not move significantly when the patient moved the finger, and therefore this test does not minimise the risk of iatrogenic tendon injury when using collagenase (Xiapex) for Dupuytren's contracture.
Citation:
Acute double flexor tendon ruptures following injection of collagenase clostridium histolyticum (Xiapex) for Dupuytren's contracture. 2014, 2014: BMJ Case Rep
Publisher:
BMJ
Journal:
BMJ case reports
Issue Date:
2014
URI:
http://hdl.handle.net/11287/619100
DOI:
10.1136/bcr-2013-203338
PubMed ID:
24729115
Additional Links:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987618/
Note:
This article is freely available via Open Access. Click on the 'Additional Link' above to access the full-text from PMC.
Type:
Case Report
Language:
en
ISSN:
1757-790X
Appears in Collections:
General Trauma & Orthopaedics; 2014 RD&E publications

Full metadata record

DC FieldValue Language
dc.contributor.authorPovlsen, B.en
dc.contributor.authorSingh, Sarvpreeten
dc.date.accessioned2016-08-31T09:12:40Z-
dc.date.available2016-08-31T09:12:40Z-
dc.date.issued2014-
dc.identifier.citationAcute double flexor tendon ruptures following injection of collagenase clostridium histolyticum (Xiapex) for Dupuytren's contracture. 2014, 2014: BMJ Case Repen
dc.identifier.issn1757-790X-
dc.identifier.pmid24729115-
dc.identifier.doi10.1136/bcr-2013-203338-
dc.identifier.urihttp://hdl.handle.net/11287/619100-
dc.description.abstractWe report a case of acute (24 h) double flexor tendon rupture of the little finger after a single injection of collagenase clostridium histolyticum into a palmar Dupuytren's contracture cord which caused metacarpophalangeal joint contracture. Tendon surgery was performed 48 h postinjury with primary repair and standard rehabilitation but it resulted in poor active flexion due to adhesions. Previous papers have suggested that a needle inserted into the flexor tendon can be detected prior to the injection of collagenase by asking the patient to actively move the finger, but our test on an awake patient showed that when a 27-gauge needle was inserted into the flexor tendons through a thick palmar cord, the syringe did not move significantly when the patient moved the finger, and therefore this test does not minimise the risk of iatrogenic tendon injury when using collagenase (Xiapex) for Dupuytren's contracture.en
dc.language.isoenen
dc.publisherBMJen
dc.relation.urlhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987618/en
dc.rightsArchived with thanks to BMJ case reportsen
dc.subjectWessex Classification Subject Headings::Orthopaedicsen
dc.subjectWessex Classification Subject Headings::Surgeryen
dc.titleAcute double flexor tendon ruptures following injection of collagenase clostridium histolyticum (Xiapex) for Dupuytren's contracture.en
dc.typeCase Reporten
dc.identifier.journalBMJ case reportsen
dc.description.noteThis article is freely available via Open Access. Click on the 'Additional Link' above to access the full-text from PMC.en
dc.type.versionPublisheden

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