Islet autoantibodies can discriminate maturity-onset diabetes of the young (MODY) from Type 1 diabetes.

2.50
Hdl Handle:
http://hdl.handle.net/11287/619205
Title:
Islet autoantibodies can discriminate maturity-onset diabetes of the young (MODY) from Type 1 diabetes.
Authors:
McDonald, Timothy J. ( 0000-0003-3559-6660 ) ; Colclough, K.; Brown, R. S.; Shields, Beverley; Shepherd, Maggie ( 0000-0003-2660-0955 ) ; Bingley, P.; Williams, A. J.; Hattersley, Andrew T.; Ellard, Sian ( 0000-0002-7620-5526 )
Abstract:
Maturity-onset diabetes of the young is a monogenic form of familial, young-onset diabetes. It is rare (∼1% diabetes) and may be misdiagnosed as Type 1 diabetes and inappropriately treated with insulin. Type 1 diabetes is characterized by the presence of islet autoantibodies, including glutamate decarboxylase (GAD) and islet antigen-2 (IA-2) antibodies. The prevalence of islet autoantibodies is unknown in maturity-onset diabetes of the young and may have the potential to differentiate this form of diabetes from Type 1 diabetes. The aim of this study was to determine the prevalence of GAD and IA-2 antibodies in patients with maturity-onset diabetes of the young and Type 1 diabetes.
Citation:
Islet autoantibodies can discriminate maturity-onset diabetes of the young (MODY) from Type 1 diabetes. 2011, 28 (9):1028-33 Diabet. Med.
Publisher:
Wiley
Journal:
Diabetic medicine : a journal of the British Diabetic Association
Issue Date:
Sep-2011
URI:
http://hdl.handle.net/11287/619205
DOI:
10.1111/j.1464-5491.2011.03287.x
PubMed ID:
21395678
Additional Links:
http://onlinelibrary.wiley.com/doi/10.1111/j.1464-5491.2011.03287.x/abstract?systemMessage=Wiley+Online+Library+will+be+unavailable+on+Saturday+3rd+September+2016+at+08.30+BST%2F+03%3A30+EDT%2F+15%3A30+SGT+for+5+hours+and+Sunday+4th+September+at+10%3A00+BST%2F+05%3A00+EST%2F+17%3A00+SGT+for+1+hour++for+essential+maintenance.+Apologies+for+the+inconvenience
Note:
This article is freely available via Open Access. Click on the ‘Additional Link’ above to access the full-text from the publisher’s site.
Type:
Research Support, Non-U.S. Gov't
Language:
en
ISSN:
1464-5491
Appears in Collections:
pre-2014 RD&E publications; Diabetes/Endocrine Services; Honorary contracts publications

Full metadata record

DC FieldValue Language
dc.contributor.authorMcDonald, Timothy J.en
dc.contributor.authorColclough, K.en
dc.contributor.authorBrown, R. S.en
dc.contributor.authorShields, Beverleyen
dc.contributor.authorShepherd, Maggieen
dc.contributor.authorBingley, P.en
dc.contributor.authorWilliams, A. J.en
dc.contributor.authorHattersley, Andrew T.en
dc.contributor.authorEllard, Sianen
dc.date.accessioned2016-09-01T10:39:42Z-
dc.date.available2016-09-01T10:39:42Z-
dc.date.issued2011-09-
dc.identifier.citationIslet autoantibodies can discriminate maturity-onset diabetes of the young (MODY) from Type 1 diabetes. 2011, 28 (9):1028-33 Diabet. Med.en
dc.identifier.issn1464-5491-
dc.identifier.pmid21395678-
dc.identifier.doi10.1111/j.1464-5491.2011.03287.x-
dc.identifier.urihttp://hdl.handle.net/11287/619205-
dc.description.abstractMaturity-onset diabetes of the young is a monogenic form of familial, young-onset diabetes. It is rare (∼1% diabetes) and may be misdiagnosed as Type 1 diabetes and inappropriately treated with insulin. Type 1 diabetes is characterized by the presence of islet autoantibodies, including glutamate decarboxylase (GAD) and islet antigen-2 (IA-2) antibodies. The prevalence of islet autoantibodies is unknown in maturity-onset diabetes of the young and may have the potential to differentiate this form of diabetes from Type 1 diabetes. The aim of this study was to determine the prevalence of GAD and IA-2 antibodies in patients with maturity-onset diabetes of the young and Type 1 diabetes.en
dc.language.isoenen
dc.publisherWileyen
dc.relation.urlhttp://onlinelibrary.wiley.com/doi/10.1111/j.1464-5491.2011.03287.x/abstract?systemMessage=Wiley+Online+Library+will+be+unavailable+on+Saturday+3rd+September+2016+at+08.30+BST%2F+03%3A30+EDT%2F+15%3A30+SGT+for+5+hours+and+Sunday+4th+September+at+10%3A00+BST%2F+05%3A00+EST%2F+17%3A00+SGT+for+1+hour++for+essential+maintenance.+Apologies+for+the+inconvenienceen
dc.rightsArchived with thanks to Diabetic medicine : a journal of the British Diabetic Associationen
dc.subjectWessex Classification Subject Headings::Endocrinology::Diabetesen
dc.titleIslet autoantibodies can discriminate maturity-onset diabetes of the young (MODY) from Type 1 diabetes.en
dc.typeResearch Support, Non-U.S. Gov'ten
dc.identifier.journalDiabetic medicine : a journal of the British Diabetic Associationen
dc.description.noteThis article is freely available via Open Access. Click on the ‘Additional Link’ above to access the full-text from the publisher’s site.en
dc.description.funding091985/Wellcome Trust/United Kingdom PDA/02/06/098/Department of Health/United Kingdomen
dc.type.versionPublisheden

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