An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation.

2.50
Hdl Handle:
http://hdl.handle.net/11287/619956
Title:
An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation.
Authors:
Hannon, Eilis; Dempster, Emma; Viana, Joana; Burrage, J.; Smith, Adam R.; Macdonald, R.; St Clair, D.; Mustard, C.; Breen, G.; Therman, S.; Kaprio, J.; Toulopoulou, T.; Hulshoff Pol, H. E.; Bohlken, M. M.; Kahn, R. S.; Nenadic, I.; Hultman, C. M.; Murray, R. M.; Collier, D. A.; Bass, N.; Gurling, H.; McQuillin, A.; Schalkwyk, L.; Mill, Jonathan
Abstract:
Schizophrenia is a highly heritable, neuropsychiatric disorder characterized by episodic psychosis and altered cognitive function. Despite success in identifying genetic variants associated with schizophrenia, there remains uncertainty about the causal genes involved in disease pathogenesis and how their function is regulated.
Citation:
An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation. 2016, 17 (1):176 Genome Biol.
Publisher:
BioMed Central
Journal:
Genome Biology
Issue Date:
30-Aug-2016
URI:
http://hdl.handle.net/11287/619956
DOI:
10.1186/s13059-016-1041-x
PubMed ID:
27572077
Additional Links:
http://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-1041-x
Note:
This article is freely available via Open Access. Click on the Additional Link above to access the full-text via the publisher's site.
Type:
Journal Article
Language:
en
ISSN:
1474-760X
Appears in Collections:
Honorary contracts publications; 2016 RD&E publications

Full metadata record

DC FieldValue Language
dc.contributor.authorHannon, Eilisen
dc.contributor.authorDempster, Emmaen
dc.contributor.authorViana, Joanaen
dc.contributor.authorBurrage, J.en
dc.contributor.authorSmith, Adam R.en
dc.contributor.authorMacdonald, R.en
dc.contributor.authorSt Clair, D.en
dc.contributor.authorMustard, C.en
dc.contributor.authorBreen, G.en
dc.contributor.authorTherman, S.en
dc.contributor.authorKaprio, J.en
dc.contributor.authorToulopoulou, T.en
dc.contributor.authorHulshoff Pol, H. E.en
dc.contributor.authorBohlken, M. M.en
dc.contributor.authorKahn, R. S.en
dc.contributor.authorNenadic, I.en
dc.contributor.authorHultman, C. M.en
dc.contributor.authorMurray, R. M.en
dc.contributor.authorCollier, D. A.en
dc.contributor.authorBass, N.en
dc.contributor.authorGurling, H.en
dc.contributor.authorMcQuillin, A.en
dc.contributor.authorSchalkwyk, L.en
dc.contributor.authorMill, Jonathanen
dc.date.accessioned2016-09-07T09:10:10Z-
dc.date.available2016-09-07T09:10:10Z-
dc.date.issued2016-08-30-
dc.identifier.citationAn integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation. 2016, 17 (1):176 Genome Biol.en
dc.identifier.issn1474-760X-
dc.identifier.pmid27572077-
dc.identifier.doi10.1186/s13059-016-1041-x-
dc.identifier.urihttp://hdl.handle.net/11287/619956-
dc.description.abstractSchizophrenia is a highly heritable, neuropsychiatric disorder characterized by episodic psychosis and altered cognitive function. Despite success in identifying genetic variants associated with schizophrenia, there remains uncertainty about the causal genes involved in disease pathogenesis and how their function is regulated.en
dc.language.isoenen
dc.publisherBioMed Centralen
dc.relation.urlhttp://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-1041-xen
dc.rightsArchived with thanks to Genome biologyen
dc.subjectWessex Classification Subject Headings::Oncology. Pathology.::Geneticsen
dc.titleAn integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation.en
dc.typeJournal Articleen
dc.identifier.journalGenome Biologyen
dc.description.noteThis article is freely available via Open Access. Click on the Additional Link above to access the full-text via the publisher's site.en
dc.type.versionPublisheden

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