Exercise capacity following a percutaneous endoscopic gastrostomy in a young female with cystic fibrosis: a case report.

2.50
Hdl Handle:
http://hdl.handle.net/11287/620068
Title:
Exercise capacity following a percutaneous endoscopic gastrostomy in a young female with cystic fibrosis: a case report.
Authors:
Tomlinson, O. W.; Barker, A. R.; Oades, Patrick ( 0000-0001-5265-6923 ) ; Williams, C. A.
Abstract:
Cystic fibrosis (CF) is a genetic condition affecting the respiratory and gastrointestinal systems, with patients experiencing problems maintaining weight, especially during rapid growth periods such as puberty. The aim of this case report was to monitor the effect of gastrostomy insertion and implementation of overnight supplemental feeding upon clinical outcomes, including body mass index (BMI), lung function (FEV1), and exercise-related variables (maximal oxygen uptake [VO2max] and ventilatory efficiency [VE/VO2]) in an 11-year-old female with CF Combined incremental and supramaximal exercise testing to exhaustion was performed at four time points: 3 months prior to the procedure (T1), 2 days prior to (T2), 4 months (T3), and 1 year following the procedure (T4). Improvements following gastrostomy insertion were observed at the 1 year follow-up with regards to BMI (+20%); whereas absolute VO2max remained stable and lung function fluctuated throughout the period of observation. Declines in function with regards to body weight relative VO2max (-16.3%) and oxygen uptake efficiency (+7.5%) were observed during this period. This case report is the first to consider exercise-related clinical outcomes in assessing the effect of implementing gastrostomy feeding in CF The varied direction and magnitude of the associations between variables shows that further investigations are required.
Citation:
Exercise capacity following a percutaneous endoscopic gastrostomy in a young female with cystic fibrosis: a case report. 2016, 4 (16) Physiol Rep
Publisher:
American Physiological Society
Journal:
Physiological Reports
Issue Date:
Aug-2016
URI:
http://hdl.handle.net/11287/620068
DOI:
10.14814/phy2.12904
PubMed ID:
27796267
Additional Links:
http://physreports.physiology.org/cgi/pmidlookup?view=long&pmid=27796267
Note:
This article is freely available via Open Access. Click on the Additional Link above to access the full-text via the publisher's site.
Type:
Case Report
Language:
en
ISSN:
2051-817X
Appears in Collections:
Paediatrics; 2016 RD&E publications

Full metadata record

DC FieldValue Language
dc.contributor.authorTomlinson, O. W.en
dc.contributor.authorBarker, A. R.en
dc.contributor.authorOades, Patricken
dc.contributor.authorWilliams, C. A.en
dc.date.accessioned2016-11-09T12:09:34Z-
dc.date.available2016-11-09T12:09:34Z-
dc.date.issued2016-08-
dc.identifier.citationExercise capacity following a percutaneous endoscopic gastrostomy in a young female with cystic fibrosis: a case report. 2016, 4 (16) Physiol Repen
dc.identifier.issn2051-817X-
dc.identifier.pmid27796267-
dc.identifier.doi10.14814/phy2.12904-
dc.identifier.urihttp://hdl.handle.net/11287/620068-
dc.description.abstractCystic fibrosis (CF) is a genetic condition affecting the respiratory and gastrointestinal systems, with patients experiencing problems maintaining weight, especially during rapid growth periods such as puberty. The aim of this case report was to monitor the effect of gastrostomy insertion and implementation of overnight supplemental feeding upon clinical outcomes, including body mass index (BMI), lung function (FEV1), and exercise-related variables (maximal oxygen uptake [VO2max] and ventilatory efficiency [VE/VO2]) in an 11-year-old female with CF Combined incremental and supramaximal exercise testing to exhaustion was performed at four time points: 3 months prior to the procedure (T1), 2 days prior to (T2), 4 months (T3), and 1 year following the procedure (T4). Improvements following gastrostomy insertion were observed at the 1 year follow-up with regards to BMI (+20%); whereas absolute VO2max remained stable and lung function fluctuated throughout the period of observation. Declines in function with regards to body weight relative VO2max (-16.3%) and oxygen uptake efficiency (+7.5%) were observed during this period. This case report is the first to consider exercise-related clinical outcomes in assessing the effect of implementing gastrostomy feeding in CF The varied direction and magnitude of the associations between variables shows that further investigations are required.en
dc.languageENG-
dc.language.isoenen
dc.publisherAmerican Physiological Societyen
dc.relation.urlhttp://physreports.physiology.org/cgi/pmidlookup?view=long&pmid=27796267en
dc.rightsArchived with thanks to Physiological Reports. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.en
dc.subjectWessex Classification Subject Headings::Paediatricsen
dc.titleExercise capacity following a percutaneous endoscopic gastrostomy in a young female with cystic fibrosis: a case report.en
dc.typeCase Reporten
dc.identifier.journalPhysiological Reportsen
dc.description.noteThis article is freely available via Open Access. Click on the Additional Link above to access the full-text via the publisher's site.en
dc.type.versionPublisheden

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