Combined treatment with regulatory T cells and vascularized bone marrow transplantation creates mixed chimerism and induces donor-specific tolerance to vascularized composite allografts without cytoreductive conditioning

2.50
Hdl Handle:
http://hdl.handle.net/11287/620130
Title:
Combined treatment with regulatory T cells and vascularized bone marrow transplantation creates mixed chimerism and induces donor-specific tolerance to vascularized composite allografts without cytoreductive conditioning
Authors:
Lin, J-Y; Tsai, F-C; Wallace, Christopher G ( 0000-0003-1897-9520 ) ; Huang, W-C; Wei, F-C; Liao, S-K
Abstract:
Cotreatment with regulatory T cells (T(reg)) and conventional allogeneic bone marrow transplantation (BMT) successfully induced durable chimerism and tolerance to nonvascularized skin allografts without cytoreductive conditioning in mice. We sought to determine whether T(reg) treatment combined with vascularized BMT (VBMT) could create mixed chimerism and induce tolerance to vascularized composite allografts (VCAs) without cytoreductive conditioning in rats.
Citation:
Combined treatment with regulatory T cells and vascularized bone marrow transplantation creates mixed chimerism and induces donor-specific tolerance to vascularized composite allografts without cytoreductive conditioning 2012, 178 (2):974 Journal of Surgical Research
Publisher:
Elsevier
Journal:
Journal of Surgical Research
Issue Date:
Dec-2012
URI:
http://hdl.handle.net/11287/620130
DOI:
10.1016/j.jss.2012.06.061
Additional Links:
http://linkinghub.elsevier.com/retrieve/pii/S0022480412006221
Type:
Journal Article
Language:
en
ISSN:
00224804
Appears in Collections:
Plastic & Reconstructive Surgery; pre-2014 RD&E publications

Full metadata record

DC FieldValue Language
dc.contributor.authorLin, J-Yen
dc.contributor.authorTsai, F-Cen
dc.contributor.authorWallace, Christopher Gen
dc.contributor.authorHuang, W-Cen
dc.contributor.authorWei, F-Cen
dc.contributor.authorLiao, S-Ken
dc.date.accessioned2017-01-04T16:11:04Z-
dc.date.available2017-01-04T16:11:04Z-
dc.date.issued2012-12-
dc.identifier.citationCombined treatment with regulatory T cells and vascularized bone marrow transplantation creates mixed chimerism and induces donor-specific tolerance to vascularized composite allografts without cytoreductive conditioning 2012, 178 (2):974 Journal of Surgical Researchen
dc.identifier.issn00224804-
dc.identifier.doi10.1016/j.jss.2012.06.061-
dc.identifier.urihttp://hdl.handle.net/11287/620130-
dc.description.abstractCotreatment with regulatory T cells (T(reg)) and conventional allogeneic bone marrow transplantation (BMT) successfully induced durable chimerism and tolerance to nonvascularized skin allografts without cytoreductive conditioning in mice. We sought to determine whether T(reg) treatment combined with vascularized BMT (VBMT) could create mixed chimerism and induce tolerance to vascularized composite allografts (VCAs) without cytoreductive conditioning in rats.en
dc.language.isoenen
dc.publisherElsevieren
dc.relation.urlhttp://linkinghub.elsevier.com/retrieve/pii/S0022480412006221en
dc.rightsArchived with thanks to Journal of Surgical Researchen
dc.subjectWessex Classification Subject Headings::Microbiology. Immunologyen
dc.titleCombined treatment with regulatory T cells and vascularized bone marrow transplantation creates mixed chimerism and induces donor-specific tolerance to vascularized composite allografts without cytoreductive conditioningen
dc.typeJournal Articleen
dc.identifier.journalJournal of Surgical Researchen
dc.type.versionPublisheden
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