Germinal centre frequency is decreased in pancreatic lymph nodes from individuals with recent-onset type 1 diabetes.

2.50
Hdl Handle:
http://hdl.handle.net/11287/620229
Title:
Germinal centre frequency is decreased in pancreatic lymph nodes from individuals with recent-onset type 1 diabetes.
Authors:
Willcox, A.; Richardson, S. J.; Walker, L. S. K.; Kent, S. C.; Morgan, Noel; Gillespie, K. M.
Abstract:
Pancreatic lymph nodes (PLNs) are critical sites for the initial interaction between islet autoantigens and autoreactive lymphocytes, but the histology of PLNs in tissue from individuals with type 1 diabetes has not been analysed in detail. The aim of this study was to examine PLN tissue sections from healthy donors compared with those at risk of, or with recent-onset and longer-duration type 1 diabetes.
Citation:
Germinal centre frequency is decreased in pancreatic lymph nodes from individuals with recent-onset type 1 diabetes. 2017 Diabetologia
Publisher:
Springer
Journal:
Diabetologia
Issue Date:
17-Feb-2017
URI:
http://hdl.handle.net/11287/620229
DOI:
10.1007/s00125-017-4221-7
PubMed ID:
28213757
Additional Links:
https://dx.doi.org/10.1007/s00125-017-4221-7
Note:
This article is freely available via Open Access. Click on the Additional Link above to access the full-text.
Type:
Journal Article
Language:
en
ISSN:
1432-0428
Appears in Collections:
Honorary contracts publications; 2017 RD&E publications

Full metadata record

DC FieldValue Language
dc.contributor.authorWillcox, A.en
dc.contributor.authorRichardson, S. J.en
dc.contributor.authorWalker, L. S. K.en
dc.contributor.authorKent, S. C.en
dc.contributor.authorMorgan, Noelen
dc.contributor.authorGillespie, K. M.en
dc.date.accessioned2017-03-01T16:02:01Z-
dc.date.available2017-03-01T16:02:01Z-
dc.date.issued2017-02-17-
dc.identifier.citationGerminal centre frequency is decreased in pancreatic lymph nodes from individuals with recent-onset type 1 diabetes. 2017 Diabetologiaen
dc.identifier.issn1432-0428-
dc.identifier.pmid28213757-
dc.identifier.doi10.1007/s00125-017-4221-7-
dc.identifier.urihttp://hdl.handle.net/11287/620229-
dc.description.abstractPancreatic lymph nodes (PLNs) are critical sites for the initial interaction between islet autoantigens and autoreactive lymphocytes, but the histology of PLNs in tissue from individuals with type 1 diabetes has not been analysed in detail. The aim of this study was to examine PLN tissue sections from healthy donors compared with those at risk of, or with recent-onset and longer-duration type 1 diabetes.en
dc.language.isoenen
dc.publisherSpringeren
dc.relation.urlhttps://dx.doi.org/10.1007/s00125-017-4221-7en
dc.rightsArchived with thanks to Diabetologiaen
dc.subjectWessex Classification Subject Headings::Endocrinology::Diabetesen
dc.titleGerminal centre frequency is decreased in pancreatic lymph nodes from individuals with recent-onset type 1 diabetes.en
dc.typeJournal Articleen
dc.identifier.journalDiabetologiaen
dc.description.noteThis article is freely available via Open Access. Click on the Additional Link above to access the full-text.en
dc.type.versionIn press (epub ahead of print)en

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