Management of thyroid eye disease in the United Kingdom: A multi-centre thyroid eye disease audit.

2.50
Hdl Handle:
http://hdl.handle.net/11287/620312
Title:
Management of thyroid eye disease in the United Kingdom: A multi-centre thyroid eye disease audit.
Authors:
Mellington, F E; Dayan, C M; Dickinson, A J; Hickey, J L; MacEwen, C J; McLaren, J; Perros, P; Rose, G E; Uddin, J; Vaidya, Bijay; Foley, P; Lazarus, J H; Mitchell, A; Ezra, D G
Abstract:
This article provides baseline data and highlight any major deficiencies in the current level of care provided for adult patients with thyroid eye disease (TED). We used prospective nonrandomized cross-sectional multicenter observational study. During a 3-month period June-August 2014, consecutive adult patients with TED who presented to nominated specialist eye clinics in the United Kingdom, completed a standardized questionnaire. Main outcome measures were: demographics, time from diagnosis to referral to tertiary centre, time from referral to review in specialist eye clinic, management of thyroid dysfunction, radioiodine and provision of steroid prophylaxis, smoking, and TED classification. 91 patients (mean age 47.88 years) were included. Female-to-male ratio was 6:1. Mean time since first symptoms of TED = 27.92 (73.71) months; from first visit to any doctor with symptoms to diagnosis = 9.37 (26.03) months; from hyperthyroidism diagnosis to euthyroidism 12.45 (16.81) months. First, 13% had received radioiodine. All those with active TED received prophylactic steroids. Seven patients who received radioiodine and did not have TED at the time went on to develop it. Then, 60% patients were current or ex-smokers. 63% current smokers had been offered smoking cessation advice. 65% patients had active TED; 4% had sight-threatening TED. A large proportion of patients (54%) were unaware of their thyroid status. Not enough patients are being provided with smoking cessation advice and information on the impact of smoking on TED and control of thyroid function.
Citation:
Management of thyroid eye disease in the United Kingdom: A multi-centre thyroid eye disease audit. 2017:1-11 Orbit
Publisher:
Taylor and Francis
Journal:
Orbit (Amsterdam, Netherlands)
Issue Date:
15-Mar-2017
URI:
http://hdl.handle.net/11287/620312
DOI:
10.1080/01676830.2017.1280057
PubMed ID:
28296512
Additional Links:
http://www.tandfonline.com/doi/full/10.1080/01676830.2017.1280057
Type:
Journal Article; Multicenter Study
Language:
en
ISSN:
1744-5108
Appears in Collections:
Diabetes/Endocrine Services; 2017 RD&E publications

Full metadata record

DC FieldValue Language
dc.contributor.authorMellington, F Een
dc.contributor.authorDayan, C Men
dc.contributor.authorDickinson, A Jen
dc.contributor.authorHickey, J Len
dc.contributor.authorMacEwen, C Jen
dc.contributor.authorMcLaren, Jen
dc.contributor.authorPerros, Pen
dc.contributor.authorRose, G Een
dc.contributor.authorUddin, Jen
dc.contributor.authorVaidya, Bijayen
dc.contributor.authorFoley, Pen
dc.contributor.authorLazarus, J Hen
dc.contributor.authorMitchell, Aen
dc.contributor.authorEzra, D Gen
dc.date.accessioned2017-03-20T10:08:18Z-
dc.date.available2017-03-20T10:08:18Z-
dc.date.issued2017-03-15-
dc.identifier.citationManagement of thyroid eye disease in the United Kingdom: A multi-centre thyroid eye disease audit. 2017:1-11 Orbiten
dc.identifier.issn1744-5108-
dc.identifier.pmid28296512-
dc.identifier.doi10.1080/01676830.2017.1280057-
dc.identifier.urihttp://hdl.handle.net/11287/620312-
dc.description.abstractThis article provides baseline data and highlight any major deficiencies in the current level of care provided for adult patients with thyroid eye disease (TED). We used prospective nonrandomized cross-sectional multicenter observational study. During a 3-month period June-August 2014, consecutive adult patients with TED who presented to nominated specialist eye clinics in the United Kingdom, completed a standardized questionnaire. Main outcome measures were: demographics, time from diagnosis to referral to tertiary centre, time from referral to review in specialist eye clinic, management of thyroid dysfunction, radioiodine and provision of steroid prophylaxis, smoking, and TED classification. 91 patients (mean age 47.88 years) were included. Female-to-male ratio was 6:1. Mean time since first symptoms of TED = 27.92 (73.71) months; from first visit to any doctor with symptoms to diagnosis = 9.37 (26.03) months; from hyperthyroidism diagnosis to euthyroidism 12.45 (16.81) months. First, 13% had received radioiodine. All those with active TED received prophylactic steroids. Seven patients who received radioiodine and did not have TED at the time went on to develop it. Then, 60% patients were current or ex-smokers. 63% current smokers had been offered smoking cessation advice. 65% patients had active TED; 4% had sight-threatening TED. A large proportion of patients (54%) were unaware of their thyroid status. Not enough patients are being provided with smoking cessation advice and information on the impact of smoking on TED and control of thyroid function.en
dc.language.isoenen
dc.publisherTaylor and Francisen
dc.relation.urlhttp://www.tandfonline.com/doi/full/10.1080/01676830.2017.1280057en
dc.rightsArchived with thanks to Orbit (Amsterdam, Netherlands)en
dc.subjectWessex Classification Subject Headings::Endocrinologyen
dc.titleManagement of thyroid eye disease in the United Kingdom: A multi-centre thyroid eye disease audit.en
dc.typeJournal Articleen
dc.typeMulticenter Studyen
dc.identifier.journalOrbit (Amsterdam, Netherlands)en
dc.type.versionIn press (epub ahead of print)en

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