The Value of Coenzyme Q10 Determination in Mitochondrial Patients.

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Authors
Yubero, D.
Allen, George
Artuch, R.
Montero, R.
Journal
Journal of clinical medicine
Type
Journal Article
Publisher
MDPI
Rights
Archived with thanks to Journal of clinical medicine
Coenzyme Q10 (CoQ) is a lipid that is ubiquitously synthesized in tissues and has a key role in mitochondrial oxidative phosphorylation. Its biochemical determination provides insight into the CoQ status of tissues and may detect CoQ deficiency that can result from either an inherited primary deficiency of CoQ metabolism or may be secondary to different genetic and environmental conditions. Rapid identification of CoQ deficiency can also allow potentially beneficial treatment to be initiated as early as possible. CoQ may be measured in different specimens, including plasma, blood mononuclear cells, platelets, urine, muscle, and cultured skin fibroblasts. Blood and urinary CoQ also have good utility for CoQ treatment monitoring.
Citation
The Value of Coenzyme Q10 Determination in Mitochondrial Patients. 2017, 6 (4) J Clin Med
Note