The Value of Coenzyme Q10 Determination in Mitochondrial Patients.

2.50
Hdl Handle:
http://hdl.handle.net/11287/620324
Title:
The Value of Coenzyme Q10 Determination in Mitochondrial Patients.
Authors:
Yubero, D.; Allen, George; Artuch, R.; Montero, R.
Abstract:
Coenzyme Q10 (CoQ) is a lipid that is ubiquitously synthesized in tissues and has a key role in mitochondrial oxidative phosphorylation. Its biochemical determination provides insight into the CoQ status of tissues and may detect CoQ deficiency that can result from either an inherited primary deficiency of CoQ metabolism or may be secondary to different genetic and environmental conditions. Rapid identification of CoQ deficiency can also allow potentially beneficial treatment to be initiated as early as possible. CoQ may be measured in different specimens, including plasma, blood mononuclear cells, platelets, urine, muscle, and cultured skin fibroblasts. Blood and urinary CoQ also have good utility for CoQ treatment monitoring.
Citation:
The Value of Coenzyme Q10 Determination in Mitochondrial Patients. 2017, 6 (4) J Clin Med
Publisher:
MDPI
Journal:
Journal of clinical medicine
Issue Date:
24-Mar-2017
URI:
http://hdl.handle.net/11287/620324
DOI:
10.3390/jcm6040037
PubMed ID:
28338638
Additional Links:
http://www.mdpi.com/resolver?pii=jcm6040037
Type:
Journal Article
Language:
en
Appears in Collections:
Exeter Clinical Laboratory International (Blood Sciences, Genetics, Cellular Pathology & Microbiology); 2017 RD&E publications

Full metadata record

DC FieldValue Language
dc.contributor.authorYubero, D.en
dc.contributor.authorAllen, Georgeen
dc.contributor.authorArtuch, R.en
dc.contributor.authorMontero, R.en
dc.date.accessioned2017-05-12T15:19:04Z-
dc.date.available2017-05-12T15:19:04Z-
dc.date.issued2017-03-24-
dc.identifier.citationThe Value of Coenzyme Q10 Determination in Mitochondrial Patients. 2017, 6 (4) J Clin Meden
dc.identifier.pmid28338638-
dc.identifier.doi10.3390/jcm6040037-
dc.identifier.urihttp://hdl.handle.net/11287/620324-
dc.description.abstractCoenzyme Q10 (CoQ) is a lipid that is ubiquitously synthesized in tissues and has a key role in mitochondrial oxidative phosphorylation. Its biochemical determination provides insight into the CoQ status of tissues and may detect CoQ deficiency that can result from either an inherited primary deficiency of CoQ metabolism or may be secondary to different genetic and environmental conditions. Rapid identification of CoQ deficiency can also allow potentially beneficial treatment to be initiated as early as possible. CoQ may be measured in different specimens, including plasma, blood mononuclear cells, platelets, urine, muscle, and cultured skin fibroblasts. Blood and urinary CoQ also have good utility for CoQ treatment monitoring.en
dc.language.isoenen
dc.publisherMDPIen
dc.relation.urlhttp://www.mdpi.com/resolver?pii=jcm6040037en
dc.rightsArchived with thanks to Journal of clinical medicineen
dc.subjectWessex Classification Subject Headings::Clinical pathologyen
dc.titleThe Value of Coenzyme Q10 Determination in Mitochondrial Patients.en
dc.typeJournal Articleen
dc.identifier.journalJournal of clinical medicineen
dc.type.versionPublisheden

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