Molecular epidemiology of Pseudomonas aeruginosa in an unsegregated bronchiectasis cohort sharing hospital facilities with a cystic fibrosis cohort.

2.50
Hdl Handle:
http://hdl.handle.net/11287/620467
Title:
Molecular epidemiology of Pseudomonas aeruginosa in an unsegregated bronchiectasis cohort sharing hospital facilities with a cystic fibrosis cohort.
Authors:
Mitchelmore, Philip J; Randall, Joanna; Bull, M. J.; Moore, K. A.; O'Neill, P.A.; Paszkiewicz, K.; Mahenthiralingam, E.; Scotton, C. J.; Sheldon, Christopher David; Withers, Nicholas J.; Brown, Alan R.
Abstract:
While Pseudomonas aeruginosa (PA) cross-infection is well documented among patients with cystic fibrosis (CF), the equivalent risk among patients with non-CF bronchiectasis (NCFB) is unclear, particularly those managed alongside patients with CF. We performed analysis of PA within a single centre that manages an unsegregated NCFB cohort alongside a segregated CF cohort. We found no evidence of cross-infection between the two cohorts or within the segregated CF cohort. However, within the unsegregated NCFB cohort, evidence of cross-infection was found between three (of 46) patients. While we do not presently advocate any change in the management of our NCFB cohort, longitudinal surveillance is clearly warranted.
Citation:
Molecular epidemiology of Pseudomonas aeruginosa in an unsegregated bronchiectasis cohort sharing hospital facilities with a cystic fibrosis cohort. 2017 Thorax
Publisher:
BMJ
Journal:
Thorax
Issue Date:
26-Aug-2017
URI:
http://hdl.handle.net/11287/620467
DOI:
10.1136/thoraxjnl-2016-209889
PubMed ID:
28844058
Additional Links:
http://thorax.bmj.com/cgi/pmidlookup?view=long&pmid=28844058
Note:
RD&E staff can access the full-text of this article. Click on the Additional Link above to access the full-text, logging in with NHS OpenAthens if prompted.
Type:
Journal Article
Language:
en
ISSN:
1468-3296
Appears in Collections:
Respiratory Medicine; Exeter Clinical Laboratory International (Blood Sciences, Genetics, Cellular Pathology & Microbiology); 2017 RD&E publications

Full metadata record

DC FieldValue Language
dc.contributor.authorMitchelmore, Philip Jen
dc.contributor.authorRandall, Joannaen
dc.contributor.authorBull, M. J.en
dc.contributor.authorMoore, K. A.en
dc.contributor.authorO'Neill, P.A.en
dc.contributor.authorPaszkiewicz, K.en
dc.contributor.authorMahenthiralingam, E.en
dc.contributor.authorScotton, C. J.en
dc.contributor.authorSheldon, Christopher Daviden
dc.contributor.authorWithers, Nicholas J.en
dc.contributor.authorBrown, Alan R.en
dc.date.accessioned2017-10-20T13:43:06Z-
dc.date.available2017-10-20T13:43:06Z-
dc.date.issued2017-08-26-
dc.identifier.citationMolecular epidemiology of Pseudomonas aeruginosa in an unsegregated bronchiectasis cohort sharing hospital facilities with a cystic fibrosis cohort. 2017 Thoraxen
dc.identifier.issn1468-3296-
dc.identifier.pmid28844058-
dc.identifier.doi10.1136/thoraxjnl-2016-209889-
dc.identifier.urihttp://hdl.handle.net/11287/620467-
dc.description.abstractWhile Pseudomonas aeruginosa (PA) cross-infection is well documented among patients with cystic fibrosis (CF), the equivalent risk among patients with non-CF bronchiectasis (NCFB) is unclear, particularly those managed alongside patients with CF. We performed analysis of PA within a single centre that manages an unsegregated NCFB cohort alongside a segregated CF cohort. We found no evidence of cross-infection between the two cohorts or within the segregated CF cohort. However, within the unsegregated NCFB cohort, evidence of cross-infection was found between three (of 46) patients. While we do not presently advocate any change in the management of our NCFB cohort, longitudinal surveillance is clearly warranted.en
dc.language.isoenen
dc.publisherBMJen
dc.relation.urlhttp://thorax.bmj.com/cgi/pmidlookup?view=long&pmid=28844058en
dc.rightsArchived with thanks to Thoraxen
dc.subjectWessex Classification Subject Headings::Respiratory medicineen
dc.subjectWessex Classification Subject Headings::Microbiology. Immunologyen
dc.titleMolecular epidemiology of Pseudomonas aeruginosa in an unsegregated bronchiectasis cohort sharing hospital facilities with a cystic fibrosis cohort.en
dc.typeJournal Articleen
dc.identifier.journalThoraxen
dc.description.noteRD&E staff can access the full-text of this article. Click on the Additional Link above to access the full-text, logging in with NHS OpenAthens if prompted.en
dc.type.versionIn press (epub ahead of print)en

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