Atypical Forms of Congenital Hyperinsulinism in Infancy Are Associated With Mosaic Patterns of Immature Islet Cells.

2.50
Hdl Handle:
http://hdl.handle.net/11287/620490
Title:
Atypical Forms of Congenital Hyperinsulinism in Infancy Are Associated With Mosaic Patterns of Immature Islet Cells.
Authors:
Han, B.; Mohamed, Z.; Estebanez, M. S.; Craigie, R. J.; Newbould, M.; Cheesman, E.; Padidela, R.; Skae, M.; Johnson, M.; Flanagan, S.; Ellard, Sian ( 0000-0002-7620-5526 ) ; Cosgrove, K. E.; Banerjee, I.; Dunne, M. J.
Abstract:
We aimed to characterize mosaic populations of pancreatic islet cells from patients with atypical congenital hyperinsulinism in infancy (CHI-A) and the expression profile of NKX2.2, a key transcription factor expressed in β-cells but suppressed in δ-cells in the mature pancreas.
Citation:
Atypical Forms of Congenital Hyperinsulinism in Infancy Are Associated With Mosaic Patterns of Immature Islet Cells. 2017, 102 (9):3261-3267 J. Clin. Endocrinol. Metab.
Publisher:
Endocrine Society
Journal:
The Journal of clinical endocrinology and metabolism
Issue Date:
1-Sep-2017
URI:
http://hdl.handle.net/11287/620490
DOI:
10.1210/jc.2017-00158
PubMed ID:
28605545
Additional Links:
https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.2017-00158
Type:
Journal Article
Language:
en
ISSN:
1945-7197
Appears in Collections:
Molecular Genetics; 2017 RD&E publications

Full metadata record

DC FieldValue Language
dc.contributor.authorHan, B.en
dc.contributor.authorMohamed, Z.en
dc.contributor.authorEstebanez, M. S.en
dc.contributor.authorCraigie, R. J.en
dc.contributor.authorNewbould, M.en
dc.contributor.authorCheesman, E.en
dc.contributor.authorPadidela, R.en
dc.contributor.authorSkae, M.en
dc.contributor.authorJohnson, M.en
dc.contributor.authorFlanagan, S.en
dc.contributor.authorEllard, Sianen
dc.contributor.authorCosgrove, K. E.en
dc.contributor.authorBanerjee, I.en
dc.contributor.authorDunne, M. J.en
dc.date.accessioned2017-11-03T16:07:32Z-
dc.date.available2017-11-03T16:07:32Z-
dc.date.issued2017-09-01-
dc.identifier.citationAtypical Forms of Congenital Hyperinsulinism in Infancy Are Associated With Mosaic Patterns of Immature Islet Cells. 2017, 102 (9):3261-3267 J. Clin. Endocrinol. Metab.en
dc.identifier.issn1945-7197-
dc.identifier.pmid28605545-
dc.identifier.doi10.1210/jc.2017-00158-
dc.identifier.urihttp://hdl.handle.net/11287/620490-
dc.description.abstractWe aimed to characterize mosaic populations of pancreatic islet cells from patients with atypical congenital hyperinsulinism in infancy (CHI-A) and the expression profile of NKX2.2, a key transcription factor expressed in β-cells but suppressed in δ-cells in the mature pancreas.en
dc.language.isoenen
dc.publisherEndocrine Societyen
dc.relation.urlhttps://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.2017-00158en
dc.rightsArchived with thanks to The Journal of clinical endocrinology and metabolismen
dc.subjectWessex Classification Subject Headings::Oncology. Pathology.::Geneticsen
dc.subject.meshBiopsy, Needle-
dc.subject.meshChild, Preschool-
dc.subject.meshCohort Studies-
dc.subject.meshCongenital Hyperinsulinism-
dc.subject.meshFemale-
dc.subject.meshGenetic Predisposition to Disease-
dc.subject.meshHumans-
dc.subject.meshImmunohistochemistry-
dc.subject.meshInfant-
dc.subject.meshIslets of Langerhans-
dc.subject.meshMale-
dc.subject.meshMosaicism-
dc.subject.meshNuclear Proteins-
dc.subject.meshPancreatectomy-
dc.subject.meshPrognosis-
dc.subject.meshReference Values-
dc.subject.meshSeverity of Illness Index-
dc.subject.meshTranscription Factors-
dc.titleAtypical Forms of Congenital Hyperinsulinism in Infancy Are Associated With Mosaic Patterns of Immature Islet Cells.en
dc.typeJournal Articleen
dc.identifier.journalThe Journal of clinical endocrinology and metabolismen
dc.type.versionPublisheden

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